Quadripulse stimulation: A replication study with a newly developed stimulator
Quadripulse stimulation: A replication study with a newly developed stimulator
复制标题
四脉冲刺激：使用新开发的刺激器进行的复制研究
DOI：
10.1016/j.brs.2022.03.006
复制
发表时间：
2022
影响因子：
7.7
通讯作者：
Amano Kaoru
中科院分区：
文献类型：
--
作者：
Kimura Ikko;Ugawa Yoshikazu;Hayashi Masamichi J.;Amano Kaoru
四脉冲刺激（QPS）是一种模式重复经颅磁刺激（rTMS）方案，可诱导长期增强（LTP）和抑郁（LTD），如后效[1]。据报道，与另一种模式的rTMS方案——θ脉冲刺激相比，QPS的后效更强，在参与者中变化更小。此外，QPS的后效不受BDNF[3]基因多态性的影响，通常影响rTMS后效[4]。因此，QPS成为神经调节研究和治疗的一种有前途的rTMS方案。最近，Deymed诊断公司开发了一种专门为QPS （DuoMAG MP-Quad, https://deymed）设计的新型刺激器。com/duomag-qps)，它似乎是一种有希望的qps刺激剂[5]。然而，DuoMAG MP-Quad诱导的后效尚未有系统的研究。考虑到不同制造商[6]的刺激脉冲波形略有不同，qps刺激器的后效程度可能有所不同。因此，我们研究了DuoMAG MP-Quad刺激器诱导的QPS后效。
Quadripulse stimulation (QPS) is a patterned repetitive transcranial magnetic stimulation (rTMS) protocol that induces long term potentiation (LTP) and depression (LTD) like after-effect [1]. The after-effect of QPS, compared to another patterned rTMS protocol–theta burst stimulation, was reported to be stronger and less variable across participants [2]. Moreover, the after-effect of QPS is not affected by gene-polymorphisms of BDNF [3], often influencing the rTMS after-effect [4]. Therefore, QPS emerges as a promising rTMS protocol for neuro-modulational research and treatment.Recently, Deymed Diagnostic has developed a new stimulator specifically designed for QPS (DuoMAG MP-Quad, https://deymed. com/duomag-qps), which appears as a promising QPS-stimulator [5]. However, the after-effect induced by the DuoMAG MP-Quad has not yet been systematically investigated. The degree of after-effect may differ between QPS-stimulators considering that the waveform of stimulation pulses slightly differs between manufacturers [6]. We thus studied the QPS after-effects induced by the DuoMAG MP-Quad stimulator.
影响因子：
4.3
作者：
M. Wessel;L. Draaisma;T. Morishita;F. Hummel
通讯作者：
M. Wessel;L. Draaisma;T. Morishita;F. Hummel
四脉冲刺激对人类运动皮层兴奋性的影响：重复研究
影响因子：
7.7
作者：
S. Simeoni;R. Hannah;D. Sato;M. Kawakami;J. Rothwell;G. Gigli
通讯作者：
G. Gigli