Angiogenesis-related molecular targets in esophageal cancer
Angiogenesis-related molecular targets in esophageal cancer
复制标题
食管癌血管生成相关分子靶点
DOI:
10.1517/13543784.2011.571203
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发表时间:
2011-04
期刊:
影响因子:
--
通讯作者:
D. Fan
中科院分区:
文献类型:
--
作者:
L. Hong;S. Li;Y. Han;J. Du;H. Zhang;J. Li;Q. Zhao;K. Wu;D. Fan
Introduction: Angiogenesis has become an appealing target in cancer therapy due to its fundamental role in cancer growth and metastasis. A number of angiogenesis-related molecules are under investigation, with some already in clinical practice with various results. The effort to present and discuss the current status of the research on the angiogenesis-related molecular targets will lead to improved clinical strategies and outcomes for patients with esophageal cancer (EC). Areas covered : This review summarizes the recent advances in angiogenesis-related targets in EC, and also analyzes the clinical and therapeutic applications they provide. We envisage future developments towards the anti-angiogenic strategy of molecular targets and their potential applications to cancer treatment. Expert opinion : Angiogenesis-related targets can be used as a useful therapeutic tool for EC. More investigations should be performed to promote the success of anti-angiogenic therapy in clinical trials.
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