Identifying barriers and facilitators of the inclusion of pregnant individuals in hepatitis C treatment programs in the United States.
Identifying barriers and facilitators of the inclusion of pregnant individuals in hepatitis C treatment programs in the United States.
复制标题
确定在美国将怀孕个体纳入丙型肝炎治疗计划的障碍和促进者。
DOI：
10.1371/journal.pone.0277987
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发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
--
作者：
The rising prevalence of hepatitis C virus (HCV) infection and the availability of direct acting antivirals for HCV treatment has prompted a public health goal of HCV eradication. Despite the availability of treatment for HCV, treatment programs have generally excluded pregnant individuals. Our objective was to query patients and clinicians to identify barriers to including pregnant individuals in HCV treatment programs. This qualitative investigation included obstetricians and previously/currently pregnant individuals with HCV. Participants completed interviews regarding knowledge of and attitudes towards HCV treatment and perceived barriers to treatment during pregnancy. Data were analyzed using the constant comparative method. Obstetricians (N = 18) and patients (N = 21) described concerns about equity, access, and cost. Both expressed uncertainty about safety and confirmed a need for clinician education. Obstetricians emphasized the lack of professional guidelines. Although some clinicians expressed concern about patient adherence and engagement, patients were largely desirous of treatment; both groups identified potential benefits of antenatal treatment. Both patients and obstetricians were generally receptive to HCV treatment in pregnancy and recognized pregnancy as an important window of opportunity for treatment. Our findings suggest the need for further research on maternal-fetal safety of HCV treatment as well as on interventions to ensure fair and appropriate access to HCV treatment for pregnant individuals.
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影响因子：
9.8
作者：
Cassimatis, Irina R.;Ayala, Laurie D.;Yee, Lynn M.
通讯作者：
Yee, Lynn M.
影响因子：
33.7
作者：
Schillie, Sarah;Wester, Carolyn;Ryerson, A. Blythe
通讯作者：
Ryerson, A. Blythe
影响因子：
9.8
作者：
McKenney KM;Martinez NG;Yee LM
通讯作者：
Yee LM
影响因子：
39.2
作者：
Ly, Kathleen N.;Jiles, Ruth B.;Holmberg, Scott D.
通讯作者：
Holmberg, Scott D.
影响因子：
3.2
作者：
GLASER, BG
通讯作者：
GLASER, BG