Functional Preservation and Oncologic Control following Robot-Assisted versus Laparoscopic Radical Prostatectomy for Intermediate- and High-Risk Localized Prostate Cancer: A Propensity Score Matched Analysis.
Functional Preservation and Oncologic Control following Robot-Assisted versus Laparoscopic Radical Prostatectomy for Intermediate- and High-Risk Localized Prostate Cancer: A Propensity Score Matched Analysis.
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机器人辅助与腹腔镜根治性前列腺切除术治疗中危和高危局限性前列腺癌后的功能保留和肿瘤控制：倾向评分匹配分析
DOI：
10.1155/2021/4375722
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发表时间：
2021
影响因子：
--
通讯作者：
Fu B
中科院分区：
文献类型：
--
作者：
Deng W;Chen R;Zhu K;Cheng X;Xiong Y;Liu W;Zhang C;Li Y;Jiang H;Zhou X;Sun T;Chen L;Liu X;Wang G;Fu B
目的评价机器人辅助前列腺癌根治术(RARP)和腹腔镜前列腺癌根治术(LRP)对中高危局限性前列腺癌(PCa)患者尿控(UC)、勃起功能和肿瘤控制的影响。232名患有中高危局限性前列腺癌的患者纳入本研究。应用倾向评分匹配法对围手术期、功能和肿瘤学结果进行分析。在匹配的队列中，RARP组的平均手术时间显著短于LRP组(p <； 0.001)。RARP组患者发生≤II级并发症的风险也低于LRP组(p = 0.036)。输血量和≥II级并发症的比例，RARP组与LRP组相似(分别为p = 0.192和p = 1.000)。两组PT3病变率和手术切缘阳性率无显著差异。在随访期内，RARP与LRP相比，UC的恢复率明显更高。在术后6个 月和末次随访时，两组患者的勃起功能也有显著差异(p = 0.013和p = 0.009)。两组在生化指标无复发生存率方面具有统计学可比性(p = 0.228)。对于中高危局限性PCa的手术治疗，RARP比LRPII级并发症的风险更低，在不影响癌症控制的情况下保留了更好的功能。
To evaluate the urinary continence (UC), erectile function, and cancer control obtained following robot-assisted radical prostatectomy (RARP) and laparoscopic radical prostatectomy (LRP) for intermediate- and high-risk localized prostate cancer (PCa). 232 patients bearing intermediate- and high-risk localized PCa were enrolled in this study. Perioperative, functional, and oncological outcomes were analyzed after applying the propensity score matched method. Within the matched cohort, the RARP group was corrected with a significantly shorter mean operative time than the LRP group (p < 0.001). Patients in the RARP arm were also at a lower risk of ≤ Grade II complications than those in the LRP group (p = 0.036). Meanwhile, the proportions of transfusion and ≥ Grade II complications in the RARP group were similar to those in the LRP group (p = 0.192 and p = 1.000, respectively). No significant differences regarding the rates of pT3 disease and positive surgical margin existed between the two groups. RARP versus LRP tended to a significantly higher percentage of UC recovery within the follow-up period. Significant differences were also found between the RARP and LRP arms in terms of erectile function at postoperative 6 months and the last follow-up (p = 0.013 and p = 0.009, respectively). Statistical comparability in biochemical recurrence-free survival was observed between the two groups (p = 0.228). For the surgical management of intermediate- and high-risk localized PCa, RARP tended to a lower risk of ≤ Grade II complications and superior functional preservation without cancer control being compromised than LRP.
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机器人辅助和腹腔镜自由基前列腺切除术后的功能和肿瘤学结果，用于局部前列腺癌，前列腺量很大：回顾性分析，最少2年随访。
影响因子：
4.7
作者：
Deng W;Liu X;Liu W;Zhang C;Zhou X;Chen L;Guo J;Wang G;Fu B
通讯作者：
Fu B
DOI：
10.1056/nejmoa1311593
发表时间：
2014-03-06
期刊：
The New England journal of medicine
影响因子：
--
作者：
Bill-Axelson A;Holmberg L;Garmo H;Rider JR;Taari K;Busch C;Nordling S;Häggman M;Andersson SO;Spångberg A;Andrén O;Palmgren J;Steineck G;Adami HO;Johansson JE
通讯作者：
Johansson JE
影响因子：
--
作者：
Jo, Jung-Ki;Hong, Sung-Kyu;Lee, Sang-Eun
通讯作者：
Lee, Sang-Eun
DOI：
10.1007/s00464-018-6499-z
发表时间：
2019-07-01
影响因子：
3.1
作者：
Asimakopoulos, Anastasios D.;Topazio, Luca;Annino, Filippo
通讯作者：
Annino, Filippo
影响因子：
6.6
作者：
Jo, Jung Ki;Jeong, Seong Jin;Lee, Sang Eun
通讯作者：
Lee, Sang Eun