Soft-tissue imaging with C-arm cone-beam CT using statistical reconstruction.
Soft-tissue imaging with C-arm cone-beam CT using statistical reconstruction.
复制标题
DOI：
10.1088/0031-9155/59/4/1005
复制
发表时间：
2014-02-21
影响因子：
3.5
通讯作者：
Siewerdsen JH
中科院分区：
文献类型：
--
作者：
Wang AS;Stayman JW;Otake Y;Kleinszig G;Vogt S;Gallia GL;Khanna AJ;Siewerdsen JH
在这项工作中，通过对软组织性能进行公平比较，评估了统计图像重建方法（如惩罚似然法（PL））与传统滤波反投影法（FBP）相比改善C型臂锥形束CT（CBCT）术中成像软组织可视化的潜力。原型移动的C形臂用于扫描拟人头部和腹部幻影以及尸体躯干，剂量大大低于诊断CT中的典型值，并且还比较了通过管电流降低和稀疏采样来降低剂量的效果。PL和FBP之间的匹配空间分辨率由体模中低对比度（~40-80 HU）球体的边缘扩散函数确定，这些球体代表软组织成像任务。发现使用非二次Huber罚分的PL相对于FBP大幅降低了噪声，特别是在较低的空间分辨率下，其中PL在所有对象中的剂量降低50%时提供的对比度噪声比FBP增加高达1.4-2.2倍。采样策略的比较表明，软组织成像受益于剂量高于~1.7 mGy时的完全采样采集，受益于剂量低于~1.0 mGy时的50%稀疏度。因此，适当的采样策略沿着通过统计重建提供的改进的低对比度可视化，证明了通过克服噪声、空间分辨率和剂量的传统权衡，将术中C形臂CBCT扩展到神经外科以及胸部和腹部手术中软组织介入的应用的潜力。
The potential for statistical image reconstruction methods such as penalized-likelihood (PL) to improve C-arm cone-beam CT (CBCT) soft-tissue visualization for intraoperative imaging over conventional filtered backprojection (FBP) is assessed in this work by making a fair comparison in relation to soft-tissue performance. A prototype mobile C-arm was used to scan anthropomorphic head and abdomen phantoms as well as a cadaveric torso at doses substantially lower than typical values in diagnostic CT, and the effects of dose reduction via tube current reduction and sparse sampling were also compared. Matched spatial resolution between PL and FBP was determined by the edge spread function of low-contrast (~40–80 HU) spheres in the phantoms, which were representative of soft-tissue imaging tasks. PL using the non-quadratic Huber penalty was found to substantially reduce noise relative to FBP, especially at lower spatial resolution where PL provides a contrast-to-noise ratio increase up to 1.4–2.2 × over FBP at 50% dose reduction across all objects. Comparison of sampling strategies indicates that soft-tissue imaging benefits from fully sampled acquisitions at dose above ~1.7 mGy and benefits from 50% sparsity at dose below ~1.0 mGy. Therefore, an appropriate sampling strategy along with the improved low-contrast visualization offered by statistical reconstruction demonstrates the potential for extending intraoperative C-arm CBCT to applications in soft-tissue interventions in neurosurgery as well as thoracic and abdominal surgeries by overcoming conventional tradeoffs in noise, spatial resolution, and dose.
登录
查看更多内容
影响因子：
3.8
作者：
Evans, Joshua D.;Politte, David G.;Williamson, Jeffrey F.
通讯作者：
Williamson, Jeffrey F.
影响因子：
3.8
作者：
Bartolac, Steven;Clackdoyle, Rolf;Jaffray, David
通讯作者：
Jaffray, David
影响因子：
10.6
作者：
Chen GH;Theriault-Lauzier P;Tang J;Nett B;Leng S;Zambelli J;Qi Z;Bevins N;Raval A;Reeder S;Rowley H
通讯作者：
Rowley H
影响因子：
1.9
作者：
Gelabert-González, M;Iglesias-Pais, M;Martínez-Rumbo, R
通讯作者：
Martínez-Rumbo, R
影响因子：
5.9
作者：
Kalender, Willi A.;Kyriakou, Yiannis
通讯作者：
Kyriakou, Yiannis