Sex-related variation in human behavior and the brain.
Sex-related variation in human behavior and the brain.
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DOI：
10.1016/j.tics.2010.07.005
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发表时间：
2010-10
影响因子：
19.9
通讯作者：
Hines, Melissa
中科院分区：
文献类型：
--
作者：
Hines, Melissa
早在妊娠第8周，男性和女性胎儿的睾酮浓度就开始不同。这种早期激素差异对大脑发育和行为产生永久性影响。当代研究表明，激素对儿童期典型性行为的发展尤其重要，包括玩具的选择，直到最近才被认为是社会文化影响的结果。产前睾酮暴露似乎也会影响性取向和性别认同，以及一些，但不是全部，与性有关的认知，运动和个性特征。神经机制负责这些神经元诱导的行为结果开始被确定，目前的证据表明，参与下丘脑和杏仁核，以及大脑半球间的连接，和皮质区参与视觉处理。
Male and female fetuses differ in testosterone concentrations beginning as early as week 8 of gestation. This early hormone difference exerts permanent influences on brain development and behavior. Contemporary research shows that hormones are particularly important for the development of sex-typical childhood behavior, including toy choices, which until recently were thought to result solely from sociocultural influences. Prenatal testosterone exposure also appears to influence sexual orientation and gender identity, as well as some, but not all, sex-related cognitive, motor and personality characteristics. Neural mechanisms responsible for these hormone-induced behavioral outcomes are beginning to be identified, and current evidence suggests involvement of the hypothalamus and amygdala, as well as interhemispheric connectivity, and cortical areas involved in visual processing.
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影响因子：
3.9
作者：
de Vries, Annelou L. C.;Noens, Ilse L. J.;Cohen-Kettenis, Peggy T.;van Berckelaer-Onnes, Ina A.;Doreleijers, Theo A.
通讯作者：
Doreleijers, Theo A.
影响因子：
5.3
作者：
Amunts, Katrin;Armstrong, Este;Zilles, Karl
通讯作者：
Zilles, Karl
影响因子：
3.5
作者：
Byne, W;Tobet, S;Jones, LB
通讯作者：
Jones, LB
影响因子：
16.4
作者：
FEINGOLD, A
通讯作者：
FEINGOLD, A
影响因子：
4
作者：
Auyeung, Bonnie;Baron-Cohen, Simon;Hackett, Gerald
通讯作者：
Hackett, Gerald