Clinical Nutrition Research and the COVID-19 Pandemic: A Scoping Review of the ASPEN COVID-19 Task Force on Nutrition Research.
Clinical Nutrition Research and the COVID-19 Pandemic: A Scoping Review of the ASPEN COVID-19 Task Force on Nutrition Research.
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DOI：
10.1002/jpen.2036
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发表时间：
2021-01
期刊：
影响因子：
--
通讯作者：
ASPEN COVID-19 Task Force on Nutrition Research
中科院分区：
文献类型：
--
作者：
Mechanick JI;Carbone S;Dickerson RN;Hernandez BJD;Hurt RT;Irving SY;Li DY;McCarthy MS;Mogensen KM;Gautier JBO;Patel JJ;Prewitt TE;Rosenthal M;Warren M;Winkler MF;McKeever L;ASPEN COVID-19 Task Force on Nutrition Research
美国肠外肠内营养学会（白杨）2019冠状病毒病（COVID-19）营养工作组进行的这项范围审查旨在审查适用于COVID-19大流行的营养研究。新出现的科学信息的快速步伐促使这项活动发现研究/知识差距。这一方法符合乔安娜·布里格斯研究所的建议。有2301篇引文被导入。其中，有439篇文章完全摘要，24篇文章类型中确定了23个主要主题领域，来源于61个国家和8个环境中的51个专业和14个人群。对营养与COVID-19之间的流行病学/机制关系进行了审查，并将结果映射到人群、干预、比较、结局和时间（PICO-T）问题。汇总数据按临床分期进行分析：COVID-19前、急性COVID-19和慢性/COVID-19后。所有PICO-T问题都发现了研究差距。值得紧急研究的营养主题包括粮食不安全/社会基础设施和跨文化因素（COVID-19前）;基于心脏代谢的慢性病、儿科、营养支持和医院基础设施（急性COVID-19）;注册营养师营养师咨询（慢性/COVID-19后）;以及营养不良和管理（所有阶段）。随机对照试验（RCTs）的缺乏尤其明显。在儿科、微量营养素、减肥手术和跨文化因素（COVID-19前）;肠内营养、蛋白质能量需求和营养血糖控制（急性COVID-19）;家庭肠内和肠外营养支持（慢性/COVID-19后）的PICO-T问题中发现了知识差距。总之，确定了紧急营养研究的多个关键领域，特别是使用RCT设计，以改善COVID-19之前，期间和之后的患者营养护理。
The purpose of this scoping review by the American Society for Parenteral and Enteral Nutrition (ASPEN) Coronavirus Disease 2019 (COVID-19) Nutrition Task Force was to examine nutrition research applicable to the COVID-19 pandemic. The rapid pace of emerging scientific information has prompted this activity to discover research/knowledge gaps. This methodology adhered with recommendations from the Joanna Briggs Institute. There were 2301 citations imported. Of these, there were 439 articles fully abstracted, with 23 main topic areas identified across 24 article types and sourced across 61 countries and 51 specialties in 8 settings and among 14 populations. Epidemiological/mechanistic relationships between nutrition and COVID-19 were reviewed and results mapped to the Population, Intervention, Comparator, Outcome, and Time (PICO-T) questions. The aggregated data were analyzed by clinical stage: pre–COVID-19, acute COVID-19, and chronic/post–COVID-19. Research gaps were discovered for all PICO-T questions. Nutrition topics meriting urgent research included food insecurity/societal infrastructure and transcultural factors (pre–COVID-19); cardiometabolic-based chronic disease, pediatrics, nutrition support, and hospital infrastructure (acute COVID-19); registered dietitian nutritionist counseling (chronic/post–COVID-19); and malnutrition and management (all stages). The paucity of randomized controlled trials (RCTs) was particularly glaring. Knowledge gaps were discovered for PICO-T questions on pediatrics, micronutrients, bariatric surgery, and transcultural factors (pre–COVID-19); enteral nutrition, protein-energy requirements, and glycemic control with nutrition (acute COVID-19); and home enteral and parenteral nutrition support (chronic/post–COVID-19). In conclusion, multiple critical areas for urgent nutrition research were identified, particularly using RCT design, to improve nutrition care for patients before, during, and after COVID-19.
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