Conditional ablation of Raptor in the male germline causes infertility due to meiotic arrest and impaired inactivation of sex chromosomes
Conditional ablation of Raptor in the male germline causes infertility due to meiotic arrest and impaired inactivation of sex chromosomes
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雄性种系中 Raptor 的条件性切除会因减数分裂停滞和性染色体失活受损而导致不育
DOI:
10.1096/fj.201700251r
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发表时间:
2017-05
期刊:
影响因子:
4.8
通讯作者:
Ye Lan
中科院分区:
文献类型:
--
作者:
Xiong Mengneng;Zhu Zhiping;Tian Suwen;Zhu Ruping;Bai Shun;Fu Kaiqiang;Davis James G.;Sun Zheng;Baur Joseph A.;Zheng Ke;Ye Lan
Rapamycin is a clinically important drug that is used in transplantation and cancer therapy but which causes a number of side effects, including male infertility. Its canonical target, mammalian target of rapamycin complex 1 (mTORC1), plays a key role in
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影响因子:
64.5
作者:
Hobbs RM;Seandel M;Falciatori I;Rafii S;Pandolfi PP
通讯作者:
Pandolfi PP
影响因子:
3.4
作者:
Sigurdur Thor Jonsson;Hlynur Armannsson
通讯作者:
Sigurdur Thor Jonsson;Hlynur Armannsson
影响因子:
11.4
作者:
通讯作者:
--
影响因子:
64.8
作者:
Cunningham, John T.;Rodgers, Joseph T.;Puigserver, Pere
通讯作者:
Puigserver, Pere
DOI:
10.1073/pnas.0406325101
发表时间:
2004-11-23
影响因子:
11.1
作者:
Khalil, AM;Boyar, FZ;Driscoll, DJ
通讯作者:
Driscoll, DJ