Global temperature constraints on Aedes aegypti and Ae. albopictus persistence and competence for dengue virus transmission.
Global temperature constraints on Aedes aegypti and Ae. albopictus persistence and competence for dengue virus transmission.
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DOI：
10.1186/1756-3305-7-338
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发表时间：
2014-07-22
影响因子：
3.2
通讯作者：
Hay SI
中科院分区：
文献类型：
--
作者：
Brady OJ;Golding N;Pigott DM;Kraemer MU;Messina JP;Reiner RC Jr;Scott TW;Smith DL;Gething PW;Hay SI
登革热是一种在过去一百年中经历了显著扩张的疾病。了解哪些因素限制了传播的分布，可以用来预测当前和未来登革热进一步扩张的限制。虽然不是唯一的因素，但温度在定义这些限制方面起着重要作用。以往试图分析温度对登革热地理分布的影响，但没有考虑其动态的年内和日变化及其对蚊子和病毒种群的累积影响。在这里，我们扩展了现有的建模框架与新的温度为基础的关系模型指数成比例的登革热病毒的基本繁殖数。该模型框架与高时空分辨率的全球温度数据相结合，模拟温度对埃及伊蚊和埃及伊蚊的影响。白纹伊蚊对登革病毒传播的持久性和能力。我们的模型预测的地区，温度预计不会允许传输和/或伊蚊持续全年。通过重新分析现有的实验数据，我们的分析表明，Ae。白纹伊蚊通常被认为是登革热的次要媒介，其病毒传播率与其主要媒介Ae相当。埃及，当Ae.白纹伊蚊传播登革病毒的能力远远超过伊蚊。埃及人。这些结果可用于分析温度和其他促成因素对登革热或其伊蚊媒介扩张的影响。我们的发现是Ae。白纹伊蚊传播登革热的能力比伊蚊强。aegypti是相反的，目前的解释登革热传播的比较罕见的建立Ae。白纹伊蚊种群这表明Ae的有限容量。白纹伊蚊传播登革病毒更多地依赖于其生态学而不是媒介能力。我们在这里明确概述的建议为昆虫学研究指出了明确的目标。
Dengue is a disease that has undergone significant expansion over the past hundred years. Understanding what factors limit the distribution of transmission can be used to predict current and future limits to further dengue expansion. While not the only factor, temperature plays an important role in defining these limits. Previous attempts to analyse the effect of temperature on the geographic distribution of dengue have not considered its dynamic intra-annual and diurnal change and its cumulative effects on mosquito and virus populations. Here we expand an existing modelling framework with new temperature-based relationships to model an index proportional to the basic reproductive number of the dengue virus. This model framework is combined with high spatial and temporal resolution global temperature data to model the effects of temperature on Aedes aegypti and Ae. albopictus persistence and competence for dengue virus transmission. Our model predicted areas where temperature is not expected to permit transmission and/or Aedes persistence throughout the year. By reanalysing existing experimental data our analysis indicates that Ae. albopictus, often considered a minor vector of dengue, has comparable rates of virus dissemination to its primary vector, Ae. aegypti, and when the longer lifespan of Ae. albopictus is considered its competence for dengue virus transmission far exceeds that of Ae. aegypti. These results can be used to analyse the effects of temperature and other contributing factors on the expansion of dengue or its Aedes vectors. Our finding that Ae. albopictus has a greater capacity for dengue transmission than Ae. aegypti is contrary to current explanations for the comparative rarity of dengue transmission in established Ae. albopictus populations. This suggests that the limited capacity of Ae. albopictus to transmit DENV is more dependent on its ecology than vector competence. The recommendations, which we explicitly outlined here, point to clear targets for entomological investigation.
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影响因子：
2.1
作者：
Braks, MAH;Honório, NA;Lounibos, LP
通讯作者：
Lounibos, LP
影响因子：
3.2
作者：
Brady OJ;Johansson MA;Guerra CA;Bhatt S;Golding N;Pigott DM;Delatte H;Grech MG;Leisnham PT;Maciel-de-Freitas R;Styer LM;Smith DL;Scott TW;Gething PW;Hay SI
通讯作者：
Hay SI
影响因子：
2.1
作者：
Benedict, Mark Q.;Levine, Rebecca S.;Lounibos, L. Philip
通讯作者：
Lounibos, L. Philip
影响因子：
2.1
作者：
Carrington, Lauren B.;Seifert, Stephanie N.;Scott, Thomas W.
通讯作者：
Scott, Thomas W.
影响因子：
4.5
作者：
Fansiri T;Fontaine A;Diancourt L;Caro V;Thaisomboonsuk B;Richardson JH;Jarman RG;Ponlawat A;Lambrechts L
通讯作者：
Lambrechts L