sFlt-1 value predicts pregnancy prolongation periods from diagnosis in pregnant women diagnosed with early-onset preeclampsia
sFlt-1 value predicts pregnancy prolongation periods from diagnosis in pregnant women diagnosed with early-onset preeclampsia
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sFlt-1 值可预测早发性先兆子痫孕妇诊断后的妊娠延长期
DOI：
10.1080/14767058.2020.1849093
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Katsuragi Shinji & Tomoaki Ikeda
中科院分区：
文献类型：
--
作者：
Hiroaki Tanaka ;Yuko Nagahashi ;Kuniaki Toriyabe ;Shintaro Maki ;Sho Takakura ;Naosuke Enomoto ;Kayo Tanaka ;Katsuragi Shinji & Tomoaki Ikeda
目的本研究的目的是分析可溶性fms样酪氨酸激酶1（sFlt-1）是否与PE的严重程度相关。材料与方法本研究是在一家医院进行的，是一项前瞻性、观察性研究。在诊断先兆子痫时测量 sFlt-1。从诊断到终止妊娠的时间（妊娠延长期）被定义为PE严重程度的晴雨表。分析sFlt-1水平与妊娠延长时间的相关性。结果纳入18例诊断为早发性子痫前期的孕妇。 sFlit-1值与诊断后妊娠延长时间显着负相关(p= .003,R= 0.647)。结论Flt-1与PE发病后妊娠延长时间相关。早发性肺栓塞中的sFlt-1可能反映孕妇肺栓塞的严重程度。
PurposeThe aim of this study is to analyze whether soluble fms-like tyrosine kinase-1 (sFlt-1) can be correlated with the severity of PE.Materials and methodsThis study was conducted in a single hospital and is a prospective, observational study. sFlt-1 was measured at the diagnosis of preeclampsia. The period from diagnosis to pregnancy termination (pregnancy prolongation periods) was defined as the barometer for the severity of PE. The correlations between sFlt-1 level with pregnancy prolongation periods were then analyzed.ResultsEighteen pregnant women diagnosed with early-onset preeclampsia were recruited. sFlit-1 value significantly negatively correlated with the pregnancy prolongation period from diagnosis (p= .003,R= 0.647).ConclusionsFlt-1 was correlated with the pregnancy prolongation periods after onset of PE. sFlt-1 in early-onset PE may reflect the severity of PE in pregnant women.
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影响因子：
158.5
作者：
Zeisler, Harald;Llurba, Elisa;Verlohren, Stefan
通讯作者：
Verlohren, Stefan
DOI：
10.1136/bmj.b2255
发表时间：
2009-06-18
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Hernández-Díaz S;Toh S;Cnattingius S
通讯作者：
Cnattingius S
影响因子：
8
作者：
M. Shibuya;S. Yamaguchi;A. Yamane;T. Ikeda;A. Tojo;H. Matsushime;Misako Sato
通讯作者：
M. Shibuya;S. Yamaguchi;A. Yamane;T. Ikeda;A. Tojo;H. Matsushime;Misako Sato
影响因子：
7.2
作者：
Lim, Ji Hyae;Kim, Shin Young;Ryu, Hyun Mee
通讯作者：
Ryu, Hyun Mee
影响因子：
158.5
作者：
Levine, Richard J.;Lam, Chun;Karumanchi, S. Ananth
通讯作者：
Karumanchi, S. Ananth