Enteric glia in homeostasis and disease: From fundamental biology to human pathology.
Enteric glia in homeostasis and disease: From fundamental biology to human pathology.
复制标题
肠神经胶质细胞在稳态和疾病:从基础生物学到人类病理学。
DOI:
10.1016/j.isci.2021.102863
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发表时间:
2021-08-20
期刊:
影响因子:
5.8
通讯作者:
Rao M
中科院分区:
文献类型:
--
作者:
Rosenberg HJ;Rao M
Glia, the non-neuronal cells of the nervous system, were long considered secondary cells only necessary for supporting the functions of their more important neuronal neighbors. Work by many groups over the past two decades has completely overturned this notion, revealing the myriad and vital functions of glia in nervous system development, plasticity, and health. The largest population of glia outside the brain is in the enteric nervous system, a division of the autonomic nervous system that constitutes a key node of the gut-brain axis. Here, we review the latest in the understanding of these enteric glia in mammals with a focus on their putative roles in human health and disease. Neuroscience; Microbiome; Gastroenterology
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