Crossmodal interactions in audiovisual emotion processing.
Crossmodal interactions in audiovisual emotion processing.
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DOI：
10.1016/j.neuroimage.2011.12.007
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发表时间：
2012-03
期刊：
影响因子：
5.7
通讯作者：
Eickhoff SB
中科院分区：
文献类型：
--
作者：
Müller VI;Cieslik EC;Turetsky BI;Eickhoff SB
日常生活中的情感往往以多模态的方式表达。因此，来自一种模态的情感信息可以影响另一种模态的处理。在之前的功能磁共振成像研究中，我们评估了视听整合的神经相关性，发现当中性刺激与情绪刺激配对时，左杏仁核的活动显着减弱，与情绪刺激同时存在于两个通道的条件相比。在这里，我们使用动态因果模型来研究这种情绪存在一致性效应背后的神经元网络中的有效连接。我们的研究结果提供了强有力的证据，有利于一个模型的家庭，不同的只是在半球间的相互作用。所有获奖模型都有一个共同点，即从双侧梭状回（FFG）到左侧杏仁核的连接，以及双侧颞后上级沟（pSTS）对这些连接的非线性调制影响。这一结果表明，pSTS不仅整合了来自视觉和听觉区域的多模态信息（如我们的模型中所反映的显著前馈连接），而且还控制了感觉信息对左杏仁核的影响，从而导致当中性刺激被整合时杏仁核活动的衰减。此外，我们发现了一个显着的偏侧化的FFG由于更强的驱动输入的刺激（面孔）到右半球，而这种偏侧化是不存在的声音驱动输入到上级颞回。总之，我们的数据提供了进一步的证据FFG的单侧化，特别是在视听情绪信息的整合和门控的pSTS的关键作用。
Emotion in daily life is often expressed in a multimodal fashion. Consequently emotional information from one modality can influence processing in another. In a previous fMRI study we assessed the neural correlates of audio–visual integration and found that activity in the left amygdala is significantly attenuated when a neutral stimulus is paired with an emotional one compared to conditions where emotional stimuli were present in both channels. Here we used dynamic causal modelling to investigate the effective connectivity in the neuronal network underlying this emotion presence congruence effect. Our results provided strong evidence in favor of a model family, differing only in the interhemispheric interactions. All winning models share a connection from the bilateral fusiform gyrus (FFG) into the left amygdala and a non-linear modulatory influence of bilateral posterior superior temporal sulcus (pSTS) on these connections. This result indicates that the pSTS not only integrates multi-modal information from visual and auditory regions (as reflected in our model by significant feed-forward connections) but also gates the influence of the sensory information on the left amygdala, leading to attenuation of amygdala activity when a neutral stimulus is integrated. Moreover, we found a significant lateralization of the FFG due to stronger driving input by the stimuli (faces) into the right hemisphere, whereas such lateralization was not present for sound-driven input into the superior temporal gyrus. In summary, our data provides further evidence for a rightward lateralization of the FFG and in particular for a key role of the pSTS in the integration and gating of audio–visual emotional information.
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影响因子：
5.7
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