Alpha oscillations do not implement gain control in early visual cortex but rather gating in parieto-occipital regions.
Alpha oscillations do not implement gain control in early visual cortex but rather gating in parieto-occipital regions.
复制标题
DOI：
10.1002/hbm.25183
复制
发表时间：
2020-12-15
影响因子：
4.8
通讯作者：
Jensen O
中科院分区：
文献类型：
--
作者：
Zhigalov A;Jensen O
空间注意分别为增强相关信息和抑制无关信息提供了一种机制。虽然注意调节α波段的振荡已经得到证实，但α振荡是否直接调节与空间注意分配相关的神经元兴奋性尚不清楚。在这项研究中，我们在人类中使用了一种新的宽带频率（60-70 Hz）标记范式来量化与空间注意范式中α振荡相关的神经元兴奋性。我们使用脑磁图来描述正在进行的大脑活动，因为它允许定位α和频率标记反应的来源。我们发现阿尔法功率的注意调制和频率标记反应在试验中是不相关的。重要的是，标记反应的神经元来源位于早期视觉皮层（V1），而α活动的来源位于顶枕沟周围。此外，我们发现注意力并没有调节频率标记反应的延迟。我们的研究结果指出，α波段振荡服务于下游门控作用，而不是实现早期视觉区域的兴奋性增益控制。通过结合脑磁图和一种新的宽带频率标记方法，我们发现空间注意不同地调节α振荡和神经元兴奋性。重要的是，α振荡和标记反应的来源在空间上是不同的，α功率和标记反应在试验中并不相关。这些结果与先前认为α振荡参与早期感觉区域增益控制的观点不一致；相反，α振荡参与下游区域神经元资源的分配。
Spatial attention provides a mechanism for, respectively, enhancing relevant and suppressing irrelevant information. While it is well established that attention modulates oscillations in the alpha band, it remains unclear if alpha oscillations are involved in directly modulating the neuronal excitability associated with the allocation of spatial attention. In this study, in humans, we utilized a novel broadband frequency (60–70 Hz) tagging paradigm to quantify neuronal excitability in relation to alpha oscillations in a spatial attention paradigm. We used magnetoencephalography to characterize ongoing brain activity as it allows for localizing the sources of both the alpha and frequency tagging responses. We found that attentional modulation of alpha power and the frequency tagging response are uncorrelated over trials. Importantly, the neuronal sources of the tagging response were localized in early visual cortex (V1) whereas the sources of the alpha activity were identified around parieto‐occipital sulcus. Moreover, we found that attention did not modulate the latency of the frequency tagged responses. Our findings point to alpha band oscillations serving a downstream gating role rather than implementing gain control of excitability in early visual regions. By combining magnetoencephalography and a novel broadband frequency tagging approach, we show that spatial attention differently modulates alpha oscillations and neuronal excitability. Importantly, the sources of the alpha oscillations and tagging responses were spatially distinct and the alpha power and tagging response were not related over trials. These results are inconsistent with previous ideas suggesting that alpha oscillations are involved in gain control of early sensory regions; rather alpha oscillations are involved in the allocation of neuronal resources in downstream regions.
登录
查看更多内容
影响因子：
5.7
作者：
Gulbinaite, Rasa;Roozendaal, Diane H. M.;VanRullen, Rufin
通讯作者：
VanRullen, Rufin
DOI：
10.1523/jneurosci.3766-09.2010
发表时间：
2010-02-24
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Lee J;Maunsell JH
通讯作者：
Maunsell JH
DOI：
10.1073/pnas.0810966105
发表时间：
2008-12-23
影响因子：
11.1
作者：
Parkkonen, Lauri;Andersson, Jesper;Hari, Riitta
通讯作者：
Hari, Riitta
影响因子：
--
作者：
Oostenveld R;Fries P;Maris E;Schoffelen JM
通讯作者：
Schoffelen JM
影响因子：
2
作者：
Portin, K;Vanni, S;Hari, R
通讯作者：
Hari, R