Effectiveness assessment of plant mixtures against Ichthyophthirius multifiliis in grass carp Ctenopharyngodon idella
Effectiveness assessment of plant mixtures against Ichthyophthirius multifiliis in grass carp Ctenopharyngodon idella
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植物混合物对抗草鱼草鱼多子鱼霉的有效性评估
DOI：
10.1016/j.aquaculture.2020.735742
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发表时间：
2021-01
期刊：
影响因子：
4.5
通讯作者：
Zhang Qi-Zhong
中科院分区：
文献类型：
--
作者：
Fu Yao-Wu;Guo Shu-Quan;Luo Jia-Ju;Sang Chi-Guo;Lin De-Jie;Liu Yan-Meng;Zhang Qi-Zhong
多丝小瓜虫是引起淡水鱼“白色斑点病”的一种纤毛寄生虫。该病的爆发给水产养殖业造成了巨大的经济损失。本研究旨在筛选出抗寄生虫效果较好的植物合剂。multifiliisandassessingplantmixtures对草鱼的毒性。筛选结果表明，白前、补骨脂、苦参、千年健、姜黄和桑树的乙醇提取物对寄生虫I.多丝的采用棋盘阵列法研究了7种植物中每两种植物组成的21个组合的加性、增效、拮抗和无差异效应。筛选出9个具有协同和相加作用的组合，用于进一步的体外、体内和急性毒性实验。最后，组合4（Com 4）含有C. atratumandS.结果表明，黄曲霉素对草鱼感染I.多丝的Com 4以6 mg/L的浓度连续用药10 d，对感染草鱼有治愈作用。对草鱼的96 h半致死浓度（LC_（50））为173.4mg/L，安全浓度（SC）为47.4mg/L。因此，Com 4是一种潜在的低毒防治植物.多丝草鱼
Ichthyophthirius multifiliis, a ciliated parasite, results in “white spot disease” of freshwater fish. The outbreak of this disease causes a significant economic loss in the aquaculture industry. The present study aimed to screen the plants mixture with high antiparasitic efficacy againstI. multifiliisand assess the toxicity of plants mixture to grass carp. The screening study indicated that ethanol extracts of Cynanchumatratum, Psoralea corylifolia,Zingiber officinale, Sophora flavescens,Homalomena occulta, Curcuma longa, and Morus alba showed antiparasitic efficacy againstI. multifiliis. Twenty-one combinations composed of every two of the seven plants were prepared to investigate their additive, synergistic, and antagonistic effects as well as indifference using the checkerboard arrays method. Nine combinations with synergistic and additive effects were screened for the furtherin vitro,in vivo, and acute toxicity experiments. Finally, combination 4 (Com 4) containingC. atratumandS. flavescensshowed high efficacy in treating grass carp infected withI. multifiliis. Com 4 at a concentration of 6 mg/L with a continuous usage for 10 days cured the infected grass carp. The 96 h median lethal concentration (LC50) of Com 4 to grass carp was 173.4 mg/L with a safe concentration (SC) of 47.4 mg/L. Thus, Com 4 has a low toxicity potential candidate to prevent and controlI. multifiliisin grass carp.
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影响因子：
1.4
作者：
Yao-wu Fu;Qi-Zhong Zhang;De-hai Xu;Bin Wang;Jing-Han Liang;D. Lin
通讯作者：
Yao-wu Fu;Qi-Zhong Zhang;De-hai Xu;Bin Wang;Jing-Han Liang;D. Lin
影响因子：
2
作者：
Ekanem, AP;Obiekezie, A;Knopf, K
通讯作者：
Knopf, K
DOI：
10.1007/978-3-540-48996-2_1568
发表时间：
2022-01
期刊：
CABI Compendium
影响因子：
--
作者：
지보영;김기홍;박수일
通讯作者：
지보영;김기홍;박수일
影响因子：
1.4
作者：
Jian-Pei Li;Yao-wu Fu;Qi-Zhong Zhang;De-hai Xu;Yan-Meng Liu;Sheng-Yu Zhou;D. Lin
通讯作者：
Jian-Pei Li;Yao-wu Fu;Qi-Zhong Zhang;De-hai Xu;Yan-Meng Liu;Sheng-Yu Zhou;D. Lin
DOI：
10.7939/r3j38kv04
发表时间：
1997-08
期刊：
The Journal of parasitology
影响因子：
--
作者：
A. O. Bush;K. Lafferty;J. Lotz;A. Shostak
通讯作者：
A. O. Bush;K. Lafferty;J. Lotz;A. Shostak