Postural studies in pulsatile ocular blood flow: I. Ocular hypertension and normotension.
Postural studies in pulsatile ocular blood flow: I. Ocular hypertension and normotension.
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脉动眼血流的姿势研究：I. 高眼压和正常血压。
DOI：
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发表时间：
1991
影响因子：
4.1
通讯作者：
S. Smith
中科院分区：
文献类型：
--
作者：
D. Trew;S. Smith
在一组健康的眼血压正常的志愿者和从门诊招募的眼高血压患者中记录了脉动眼血流量（POBF）的测量。使用一个与朗廷眼血流系统相连的测气探头，可以在直立和仰卧时读取眼压及其随心率（眼脉搏）的变化。脉动眼血流量是通过先前描述的活人眼睛的压力-体积关系从这些值计算出来的。假定为仰卧位时，眼压显著升高；正常眼（扫描电镜平均值）（3.1 (0.4)mmHg, p < 0.0001），高眼压眼（4.7 (0.6)mmHg, p < 0.0001）。无论是直立姿势还是仰卧姿势，正常血压组和高眼压组之间的POBF均无显著差异。然而，在两组中，假设仰卧位都伴随着POBF的显著下降(正常值：-121（21）微升/分钟，p小于0.0001；高眼压：-75（16）微升/分钟，p < 0.0002)。POBF的减少幅度分别为27.5%(3.0)%和17.1%(3.8)%。仰卧位时，眼部搏动血流量减少，这可能导致有青光眼风险的受试者组织缺氧。另一篇论文描述了一组使用局部替莫洛尔0.25%治疗的慢性开角型青光眼患者的POBF测量。
Measurements of pulsatile ocular blood flow (POBF) have been recorded in a group of healthy, ocular normotensive volunteers and ocular hypertensive patients recruited from outpatients. Use of a pneumotonometric probe linked to a Langham ocular blood flow system enabled readings of intraocular pressure and its variation with heart rate (ocular pulse) to be taken in erect and supine positions. Pulsatile ocular blood flow was calculated from these values by means of the pressure-volume relationship previously described for living human eyes. Assumption of the supine posture was accompanied by a significant rise in intraocular pressure; in normal eyes (mean, with SEM) (3.1 (0.4) mmHg, p less than 0.0001) and to a greater extent in ocular hypertensive eyes (4.7 (0.6) mmHg, p less than 0.0001). The POBF did not differ significantly between normotensive and ocular hypertensive groups in either the erect or supine postures. In both groups, however, assumption of the supine posture was accompanied by a significant fall in POBF (normals: -121 (21) microliters/min, p less than 0.0001; ocular hypertensives: -75 (16) microliters/min, p less than 0.0002). These reductions in POBF represent decrements of 27.5 (3.0)% and 17.1 (3.8)% respectively. Pulsatile ocular blood flow is reduced in the supine posture, and this may result in tissue hypoxia in subjects at risk of developing glaucoma. A companion paper describes the measurement of POBF in a group of patients with chronic open angle glaucoma treated with topical timolol 0.25%.
影响因子：
4.4
作者：
C. Riva;J. Grunwald;S. Sinclair;B. Petrig
通讯作者：
C. Riva;J. Grunwald;S. Sinclair;B. Petrig
激光多普勒测量人体视神经乳头的相对血流速度。
影响因子：
4.4
作者：
Riva,CE;Grunwald,JE;Sinclair,SH
通讯作者：
Sinclair,SH
使用放射性标记微球观察狗的眼部血流。
DOI：
10.1016/0883-2897(89)90217-1
发表时间：
1989
期刊：
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology
影响因子：
--
作者：
Roy,MS;Harrison,KS;Harvey,E;Mitchell,T
通讯作者：
Mitchell,T