Improved voluntary cough immediately following office-based vocal fold medialization injections.
Improved voluntary cough immediately following office-based vocal fold medialization injections.
复制标题
在办公室进行声带内侧注射后，自觉咳嗽立即得到改善。
DOI：
10.1002/lary.24529
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Sapienza,ChristineM
中科院分区：
文献类型：
--
作者：
Ruddy,BariH;Pitts,TeresaE;Lehman,Jeff;Spector,Brian;Lewis,Vicki;Sapienza,ChristineM
目的/假设：本研究检查了诊断为声门不全的患者在办公室注射Radiesse后立即自发性咳嗽气流测量的变化。由于明显的合并症，这些患者不适合在全身麻醉下进行麻醉。每位患者均表现为发音困难和吞咽困难以及无效的自主咳嗽，导致分泌物清除不良和检查时出现摄入液体。研究设计前瞻性队列和病例系列研究。方法对3例诊断为声门功能不全的患者进行软性内窥镜和频闪喉镜检查。在Radiesse注射前后约30分钟进行自愿咳嗽气流测量。气流测量包括：压缩期持续时间（CPD）、呼气上升时间（EPRT）、呼气期气流峰值（EPPF）和咳嗽量加速（CVA）。结果注射Radiesse可改善自发性咳嗽气流测量。结论注射Radiesse后自发性咳嗽的客观气流测量立即增加，可用于证明气道保护的改善。咳嗽气流是一种直观的测量方法，被认为是咳嗽功能的客观测量方法。证据水平喉镜，24 (4):645 - 647,2014
Objectives/HypothesisThis study examined changes in voluntary cough airflow measures immediately following in‐office injection of Radiesse in patients diagnosed with glottic insufficiency. Due to significant comorbidities, these patients were poor candidates for medialization under general anesthesia. Each patient presented with dysphonia and dysphagia and ineffective voluntary cough, resulting in a poor clearing of secretions and a presence of ingested fluids on examination.Study DesignProspective cohort and case series study.MethodsThree patients with a diagnosis of glottic insufficiency were included for study based on flexible endoscopy and laryngostroboscopic examination. Voluntary cough airflow measures were obtained approximately 30 minutes before and after the Radiesse injections. The airflow measures were: compression phase duration (CPD), expiratory rise time (EPRT), expiratory phase peak airflow (EPPF), and cough volume acceleration (CVA).ResultsInjection of Radiesse was found to improve voluntary cough airflow measures.ConclusionThe immediate increase in the objective airflow measures obtained from voluntary cough production after Radiesse injections can be used to document airway protection improvements. Cough airflow is a straightforward measure to obtain and is considered an objective measure of cough function.Level of Evidence4.Laryngoscope, 124:1645–1647, 2014
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影响因子：
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DOI：
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发表时间：
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期刊：
The Journal of experimental medicine
影响因子：
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