Stimulation by inositol trisphosphate and tetrakisphosphate of a protein phosphatase.

Stimulation by inositol trisphosphate and tetrakisphosphate of a protein phosphatase.
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蛋白磷酸酶的肌醇三磷酸和四磷酸刺激。

DOI:
10.1016/s0006-291x(88)80561-8
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发表时间:
1988
影响因子:
3.1
通讯作者:
Boynton,AL
Boynton,AL
中科院分区:
生物学4区
文献类型:
--
作者:
Zwiller,J;Ogasawara,EM;Nakamoto,SS;Boynton,AL

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几种肌醇三磷酸异构体和肌醇四磷酸激活大鼠脑磷蛋白磷酸酶,使用磷酸化组蛋白以及磷酸化酶激酶作为底物。肌醇一磷酸和二磷酸没有影响。蛋白磷酸酶可能对应于1型,因为它与颗粒部分相关,并被肝素抑制。证据是磷酸肌醇作为蛋白磷酸酶的催化亚基的目标。观察到几种三磷酸肌醇激活蛋白磷酸酶的能力与表明其在透化细胞中释放钙的能力的报告数据之间的平行性。
Several inositol trisphosphate isomers and inositol tetrakisphosphate activate a rat brain phosphoprotein phosphatase, using phosphohistone as well as phosphorylase kinase as substrate. Inositol mono- and bisphosphate have no effect. The protein phosphatase may corespond to type-1 since it is associated with the particulate fraction and is inhibited by heparin. Evidence is presented for the target of inositol phosphate being the catalytic subunit of the protein phosphatase. A parallelism is observed between the ability of the several inositol trisphosphates to activate the protein phosphatase and reported data indicating their ability to release calcium in permeabilized cells.
肌醇三磷酸诱导透化瑞士小鼠 3T3 细胞钙释放的特异性。
DOI: --
发表时间: 1984
影响因子: 4.1
作者:
R. Irvine;K. Brown;M. Berridge
通讯作者: M. Berridge
DOI: --
发表时间: 1974
期刊: Biochemical and Biophysical Research Communications - BBRC
影响因子: --
作者:
H. Brandt;S. Killilea;Ernest Y.C. Lee
通讯作者: Ernest Y.C. Lee
从兔骨骼肌中分离两种磷酸化酶激酶磷酸酶。
DOI: --
发表时间: 1976
期刊: European Journal of Biochemistry
影响因子: --
作者:
J. Antoniw;P. Cohen
通讯作者: P. Cohen
DOI: 10.1126/science.3024320
发表时间: 1986-12-19
期刊: SCIENCE
影响因子: 56.9
作者:
MAJERUS, PW;CONNOLLY, TM;WILSON, DB
通讯作者: WILSON, DB
1 型和 2 型蛋白磷酸酶催化亚基均可结合抑制剂 2 和单克隆免疫球蛋白。
DOI: --
发表时间: 1986
期刊: The Journal of biological chemistry
影响因子: --
作者:
Brautigan,DL;Gruppuso,PA;Mumby,M
通讯作者: Mumby,M