Synthesis of nitric oxide in the bovine retina.
Synthesis of nitric oxide in the bovine retina.
复制标题
牛视网膜中一氧化氮的合成。
DOI:
10.1016/s0006-291x(05)81153-2
复制
发表时间:
1991
影响因子:
3.1
通讯作者:
Moncada,S
中科院分区:
文献类型:
--
作者:
Venturini,CM;Knowles,RG;Palmer,RM;Moncada,S
In the absence of light, high concentrations of cGMP open ion channels in the plasma membranes of rod outer segments. The source of stimulation of retinal guanylate cyclase is not known. Nitric oxide is a potent stimulator of guanylate cyclase in other cell systems. The present data demonstrate that nitric oxide synthase, an enzyme responsible for the production of nitric oxide, is present in retina, and specifically in the rod outer segments. This enzyme uses L-arginine as a substrate and is NADPH- and calcium- dependent. L-arginine-derived nitric oxide may be a source of activation of guanylate cyclase in the retina.
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DOI:
--
发表时间:
1991
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Stryer,L
通讯作者:
Stryer,L
DOI:
--
发表时间:
1991
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Horio,Y;Murad,F
通讯作者:
Murad,F
DOI:
10.1096/fasebj.4.12.1697545
发表时间:
1990
期刊:
The FASEB Journal
影响因子:
--
作者:
R. Lolley;Rehwa H. Lee
通讯作者:
Rehwa H. Lee
影响因子:
3.4
作者:
Williams,DS;Shuster,TA;Moldrawski,MR;Blest,AD;Farber,DB
通讯作者:
Farber,DB
DOI:
10.1016/s0006-291x(89)80037-3
发表时间:
1989-12-15
影响因子:
3.1
作者:
PALACIOS, M;KNOWLES, RG;MONCADA, S
通讯作者:
MONCADA, S