Both Conifer II and Gnetales are characterized by a high frequency of ancient mitochondrial gene transfer to the nuclear genome.
Both Conifer II and Gnetales are characterized by a high frequency of ancient mitochondrial gene transfer to the nuclear genome.
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针叶树 II 和买麻藤目的特点是古代线粒体基因转移到核基因组的频率很高
DOI：
10.1186/s12915-021-01096-z
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发表时间：
2021-07-28
期刊：
影响因子：
5.4
通讯作者：
Wang XQ
中科院分区：
文献类型：
--
作者：
Kan SL;Shen TT;Ran JH;Wang XQ
线粒体基因转移/丢失在陆生植物中普遍存在，因此缺失线粒体基因的命运越来越受到人们的关注。裸子植物线粒体的基因含量差异很大，为研究缺失的线粒体基因的进化命运提供了一个系统。在这里，我们研究的克里思和模式的线粒体基因转移/损失的裸子植物代表的所有13个家庭，使用高通量测序的DNA和cDNA。所有41个线粒体蛋白编码基因在苏铁类、银杏类和松科中均被发现，而多个线粒体基因在针叶树II和买麻藤类中缺失。在针叶树II中，基因从线粒体转移到细胞核，随后线粒体拷贝丢失是常见的，但线粒体和细胞核基因组中的基因完全丢失是罕见的。买麻藤属植物中普遍存在基因转移和丢失现象。值得注意的是，在针叶树II和买麻藤目中，相同的五个线粒体基因被转移到核基因组中，这些基因转移事件分别发生在两个谱系的祖先中。一个两步转移机制（后处理和随后的DNA介导的基因转移）可能是负责在针叶树II和买麻藤类线粒体基因转移。此外，陆生植物线粒体基因含量的变异与基因长度、GC含量、疏水性和核苷酸替换率相关。本研究揭示了裸子植物线粒体基因转移变异的完整进化过程，以及陆生植物线粒体基因含量变异的原因。在线版本包含补充材料，可通过10.1186/s12915-021-01096-z获得。
Mitochondrial gene transfer/loss is common in land plants, and therefore the fate of missing mitochondrial genes has attracted more and more attention. The gene content of gymnosperm mitochondria varies greatly, supplying a system for studying the evolutionary fate of missing mitochondrial genes. Here, we studied the tempo and pattern of mitochondrial gene transfer/loss in gymnosperms represented by all 13 families, using high-throughput sequencing of both DNA and cDNA. All 41 mitochondrial protein-coding genes were found in cycads, Ginkgo and Pinaceae, whereas multiple mitochondrial genes were absent in Conifer II and Gnetales. In Conifer II, gene transfer from mitochondria to the nucleus followed by loss of the mitochondrial copy was common, but complete loss of a gene in both mitochondrial and nuclear genomes was rare. In contrast, both gene transfer and loss were commonly found in Gnetales. Notably, in Conifer II and Gnetales, the same five mitochondrial genes were transferred to the nuclear genome, and these gene transfer events occurred, respectively, in ancestors of the two lineages. A two-step transfer mechanism (retroprocessing and subsequent DNA-mediated gene transfer) may be responsible for mitochondrial gene transfer in Conifer II and Gnetales. Moreover, the mitochondrial gene content variation is correlated with gene length, GC content, hydrophobicity, and nucleotide substitution rates in land plants. This study reveals a complete evolutionary scenario for variations of mitochondrial gene transferring in gymnosperms, and the factors responsible for mitochondrial gene content variation in land plants. The online version contains supplementary material available at 10.1186/s12915-021-01096-z.
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影响因子：
10.7
作者：
Chaw, Shu-Miaw;Shih, Arthur Chun-Chieh;Chou, The-Yuan
通讯作者：
Chou, The-Yuan
影响因子：
3.7
作者：
Dong, Shanshan;Chen, Lu;Zhang, Shouzhou
通讯作者：
Zhang, Shouzhou
影响因子：
9.3
作者：
Johnston, Iain G.;Williams, Ben P.
通讯作者：
Williams, Ben P.
影响因子：
10.7
作者：
Berg, OG;Kurland, CG
通讯作者：
Kurland, CG
DOI：
10.1073/pnas.042694899
发表时间：
2002-07-23
影响因子：
11.1
作者：
Adams, KL;Qiu, YL;Palmer, JD
通讯作者：
Palmer, JD