Probing the influence of post-processing on microstructure and in situ compression failure with in silico modeling of 3D-printed scaffolds
Probing the influence of post-processing on microstructure and in situ compression failure with in silico modeling of 3D-printed scaffolds
复制标题
通过 3D 打印支架的计算机建模探讨后处理对微观结构和原位压缩失效的影响
DOI：
10.1557/jmr.2018.188
复制
发表时间：
2018
影响因子：
2.7
通讯作者：
B. Basu
中科院分区：
文献类型：
--
作者：
Sourav Mandal;B. Basu
后加工处理在定制三维粉末打印多孔支架的机械和生物性能方面起着重要作用。根据支架材料的组成，可以使用后加工处理的组合来定制这些特性。这项工作探讨了后处理对3D打印支架的微观结构和变形行为的影响。在这项研究中，我们选择了CaSO_4·xH_2O（POP），一个用于3D粉末打印的系统和两种不同的后处理方法，即化学转化和聚合物渗透。POP为基础的支架制作使用水基粘合剂高达55%的互连微孔和1.5 MPa的中等压缩强度。微计算机断层扫描（µCT）被广泛用于确定所采用的打印和后处理方法的准确性和有效性。结果表明，精细特征的再现性不仅取决于尺寸，而且取决于相邻特征的存在。至关重要的是，基于µ CT的微观结构建模和有限元模拟试图通过计算机模拟计算捕获压缩行为。最后，原位压缩结合µCT成像为我们提供了对3D粉末打印支架断裂行为的深入了解。
The post-processing treatment plays an important role in tailoring the mechanical and biological properties of the three-dimensional powder-printed porous scaffolds. Depending on scaffold material composition, a combination of post-processing treatments can be used to tailor these properties. This work probes into the impact of post-processing on the microstructure and deformation behavior of 3D-printed scaffolds. In this study, we have chosen CaSO_4· x H_2O (POP), a system for 3D powder printing and two different post-processing methodologies, namely chemical conversion and polymer infiltration. POP-based scaffolds were fabricated using water-based binder with up to 55% interconnected microporosity and moderate compressive strength of 1.5 MPa. Microcomputed tomography (µCT) is extensively utilized to determine the accuracy and efficacy of the adopted printing and post-processing approach. It was shown that the reproducibility of the fine features depends not only on the size but also on the presence of neighboring features. Crucially, µCT-based microstructure modeling and finite elemental simulation were attempted to computationally capture the compression behavior, in silico. Finally, in situ compression coupled with µCT imaging provided us an insight into fracture behavior of 3D powder-printed scaffolds.
DOI：
10.1002/jbm.b.31464
发表时间：
2009-11
影响因子：
3.4
作者：
Xue, Weichang;Bandyopadhyay, Amit;Bose, Susmita
通讯作者：
Bose, Susmita