Enhancement of anti-tumor immunity by photodynamic therapy.
Enhancement of anti-tumor immunity by photodynamic therapy.
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DOI:
10.1007/s12026-009-8119-4
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发表时间:
2010-03
影响因子:
4.4
通讯作者:
Brackett CM
中科院分区:
文献类型:
--
作者:
Gollnick SO;Brackett CM
Photodynamic therapy (PDT) is an FDA-approved modality that rapidly eliminates local tumors, resulting in cure of early disease and palliation of advanced disease. PDT was originally considered to be a local treatment; however, both pre-clinical and clinical studies have shown that local PDT treatment of tumors can enhance systemic anti-tumor immunity. The current state of investigations into the ability of PDT to enhance anti-tumor immunity, the mechanisms behind this enhancement and the future of PDT as an immunotherapy are addressed in this review.
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