Electrochemical solid phase micro-extraction and determination of salicylic acid from blood samples by cyclic voltammetry and differential pulse voltammetry
Electrochemical solid phase micro-extraction and determination of salicylic acid from blood samples by cyclic voltammetry and differential pulse voltammetry
复制标题
电化学固相微萃取循环伏安法和微分脉冲伏安法测定血样中的水杨酸
DOI：
10.1007/s10008-008-0707-z
复制
发表时间：
2009-09
影响因子：
2.5
通讯作者：
Zhu, Yongchun
中科院分区：
文献类型：
--
作者：
Guan, Xinyan;Ji, Hongguo;Zhu, Yongchun
采用循环伏安法研究了水杨酸在石墨-环氧复合固体电极表面的电化学固相微萃取行为。SA在pH 12.0的水溶液中于0.70 V（vs.饱和甘汞电极）电化学氧化7 s。氧化产物显示出两个表面控制的可逆氧化还原对，其中两个质子在pH 1.0 - 6.0范围内转移，一个质子在pH 10.0 - 13.0范围内转移，并且在电极表面上被萃取，动力学Boltzman函数为fip = 3.473-4.499/[1 + e（t-7.332）/6.123]（χ2= 0.00285 μA）。在5.00 μM ~ 200 μM范围内，SA浓度与峰电流呈线性关系，回归方程为：p =-5.913 +0.4843c（R= 0.995，SD = 1.6 μA）。方法的检出限为5.00 μM，相对标准偏差为1.59%（60 μM）。该方法灵敏度高、操作简便，用于小鼠血液样品中水杨酸的测定，结果满意。
The electrochemical solid phase micro-extraction of salicylic acid (SA) at graphite-epoxy-composed solid electrode surface was studied by cyclic voltammetry. SA was oxidized electrochemically in pH 12.0 aqueous solution at 0.70 V (vs. saturated calomel electrode) for 7 s. The oxidized product shows two surface-controlled reversible redox couples with two proton transferred in the pH range of 1.0∼6.0 and one proton transferred in the pH range of 10.0∼13.0 and is extracted on the electrode surface with a kinetic Boltzman function ofip= 3.473–4.499/[1 + e(t− 7.332)/6.123] (χ2= 0.00285 μA). The anodic peak current of the extracted specie in differential pulse voltammograms is proportional to the concentration of SA with regression equation ofip= −5.913 + 0.4843c(R= 0.995, SD = 1.6 μA) in the range of 5.00∼200 μM. The detection limit is 5.00 μM with RSD of 1.59% at 60 μM. The method is sensitive and convenient and was applied to the detection of SA in mouse blood samples with satisfactory results.
登录
查看更多内容
影响因子：
3.9
作者：
M. Gattrell;D. Kirk
通讯作者：
M. Gattrell;D. Kirk
DOI：
10.1039/ac9963300361
发表时间：
1996
期刊：
Analytical Communications
影响因子：
--
作者：
Feng Guo;T. Górecki;D. Irish;J. Pawliszyn
通讯作者：
Feng Guo;T. Górecki;D. Irish;J. Pawliszyn
影响因子：
2.5
作者：
Haodan Yuan;Zoltán Mester;H. Lord;Janusz Pawliszyn
通讯作者：
Haodan Yuan;Zoltán Mester;H. Lord;Janusz Pawliszyn
DOI：
10.1002/jhrc.1240180305
发表时间：
1995-03
期刊：
Hrc-journal of High Resolution Chromatography
影响因子：
--
作者：
T. Górecki;J. Pawliszyn
通讯作者：
T. Górecki;J. Pawliszyn
影响因子：
4.1
作者：
Peñalver, A;Pocurull, E;Marcé, RM
通讯作者：
Marcé, RM