Residential proximity to traffic and adverse birth outcomes in Los Angeles county, California, 1994-1996.
Residential proximity to traffic and adverse birth outcomes in Los Angeles county, California, 1994-1996.
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DOI：
10.1289/ehp.5688
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发表时间：
2003-02
影响因子：
10.4
通讯作者：
Ritz B
中科院分区：
文献类型：
--
作者：
Wilhelm M;Ritz B
我们之前曾报道，洛杉矶盆地环境空气污染的增加增加了低体重和早产的风险。然而，在监测站测量的环境浓度可能没有考虑到在交通繁忙的道路附近发现的高浓度污染物的不同暴露。因此，我们使用流行病学病例对照研究设计来检验1994至1996年间洛杉矶县居民区靠近交通繁忙的道路是否影响低出生体重(LBW)和/或早产的发生。我们绘制了受试者出生时的家庭位置图，并使用距离加权交通密度(DWTD)测量来估计与交通相关的空气污染的暴露。这一措施考虑了住宅与住宅周围道路的距离和交通水平。我们计算了LBW和/或DWTD中每五分之一早产的优势比(OR)和风险比(RR)。观察到最明显的暴露-反应模式是早产，DWTD五分位数最高的婴儿的RR为1.08[95%可信区间(CI)1.01-1.15]。虽然观察到LBW婴儿的风险更高，但暴露-反应关系不太一致。研究季节的影响，我们发现，主要是在秋季/冬季怀孕晚期的妇女风险增加(OR(长期LBW)=1.39；95%CI，1.16-1.67；OR(早产和LBW)=1.24；95%CI=1.03-1.48；RR(全部早产)=1.15；95%CI，1.05-1.26)，所有结果的暴露-反应关系更强。这一结果与冬季几个月较为停滞的空气条件下污染源附近的污染加剧是一致的。我们之前的研究和这些最新的结果表明，暴露在与交通相关的污染物中可能是重要的。
We reported previously that increases in ambient air pollution in the Los Angeles basin increased the risk of low weight and premature birth. However, ambient concentrations measured at monitoring stations may not take into account differential exposure to pollutants found in elevated concentrations near heavy-traffic roadways. Therefore, we used an epidemiologic case-control study design to examine whether residential proximity to heavy-traffic roadways influenced the occurrence of low birth weight (LBW) and/or preterm birth in Los Angeles County between 1994 and 1996. We mapped subject home locations at birth and estimated exposure to traffic-related air pollution using a distance-weighted traffic density (DWTD) measure. This measure takes into account residential proximity to and level of traffic on roadways surrounding homes. We calculated odds ratios (ORs) and risk ratios (RRs) for being LBW and/or preterm per quintile of DWTD. The clearest exposure-response pattern was observed for preterm birth, with an RR of 1.08 [95% confidence interval (CI), 1.01-1.15] for infants in the highest DWTD quintile. Although higher risks were observed for LBW infants, exposure-response relations were less consistent. Examining the influence of season, we found elevated risks primarily for women whose third trimester fell during fall/winter months (OR(term LBW) = 1.39; 95% CI, 1.16-1.67; OR(preterm and LBW) = 1.24; 95% CI = 1.03-1.48; RR(all preterm) = 1.15; 95% CI, 1.05-1.26), and exposure-response relations were stronger for all outcomes. This result is consistent with elevated pollution in proximity to sources during more stagnant air conditions present in winter months. Our previous research and these latest results suggest exposure to traffic-related pollutants may be important.
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影响因子：
5
作者：
Kingham, S;Briggs, D;Lebret, E
通讯作者：
Lebret, E
DOI：
10.1080/00022470.1977.10470453
发表时间：
1977-01-01
期刊：
JOURNAL OF THE AIR POLLUTION CONTROL ASSOCIATION
影响因子：
--
作者：
OTT, WR
通讯作者：
OTT, WR
影响因子：
4.9
作者：
Janssen, NAH;Hoek, G;Brunekreef, B
通讯作者：
Brunekreef, B
DOI：
10.1080/10473289.1990.10466754
发表时间：
1990-08-01
影响因子：
2.7
作者：
LAWSON, DR;GROBLICKI, PJ;GUENTHER, PL
通讯作者：
GUENTHER, PL
影响因子：
5
作者：
Ritz, B;Yu, F;Harris, JA
通讯作者：
Harris, JA