A review: therapeutic potential of adipose-derived stem cells in cutaneous wound healing and regeneration.
A review: therapeutic potential of adipose-derived stem cells in cutaneous wound healing and regeneration.
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综述：脂肪干细胞在皮肤伤口愈合和再生中的治疗潜力
DOI：
10.1186/s13287-018-1044-5
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发表时间：
2018-11-08
影响因子：
7.5
通讯作者：
Guo X
中科院分区：
文献类型：
--
作者：
Li P;Guo X
皮肤作为人体最重要的屏障，经常遭受急慢性损伤，尤其是难治性伤口，严重影响患者的生活质量。对于这些各种手术方法都无法治愈的难治性创面，干细胞移植成为一个有效的研究方向。脂肪源性干细胞作为成体干细胞的一种，由于其具有免疫相容性和不受伦理约束等优点，在皮肤创面修复中发挥着比其他干细胞更重要的作用。在此，我们积极探索脂肪源性干细胞在皮肤创面修复中的作用，并得出结论认为它可以显著促进皮肤创面愈合和再生。基于大量的动物和临床试验，我们相信脂肪源性干细胞在未来的皮肤创面修复领域，特别是在慢性难治性创面修复方面将会有更大的突破。
As the most important barrier for the human body, the skin often suffers from acute and chronic injuries, especially refractory wounds, which seriously affect the quality of life of patients. For these refractory wounds that cannot be cured by various surgical methods, stem cell transplantation becomes an effective research direction. As one of the adult stem cells, adipose-derived stem cells play an indispensable role in the repair of skin wounds more than other stem cells because of their advantages such as immune compatibility and freedom from ethical constraints. Here, we actively explore the role of adipose-derived stem cells in the repair of cutaneous wound and conclude that it can significantly promote cutaneous wound healing and regeneration. Based on a large number of animal and clinical trials, we believe that adipose-derived stem cells will have a greater breakthrough in the field of skin wound repair in the future, especially in chronic refractory wounds.
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影响因子：
6
作者：
Garg, Ravi K.;Rennert, Robert C.;Gurtner, Geoffrey C.
通讯作者：
Gurtner, Geoffrey C.
DOI：
10.1161/atvbaha.108.178962
发表时间：
2009-04-01
影响因子：
8.7
作者：
Ebrahimian, T. G.;Pouzoulet, F.;Tamarat, R.
通讯作者：
Tamarat, R.
影响因子：
3.9
作者：
Herreros, M. D.;Garcia-Arranz, M.;Garcia-Olmo, D.
通讯作者：
Garcia-Olmo, D.
影响因子：
6.2
作者：
Cerqueira, M. T.;Pirraco, R. P.;Marques, A. P.
通讯作者：
Marques, A. P.
影响因子：
15.9
作者：
BUSSOLINO, F;ZICHE, M;MANTOVANI, A
通讯作者：
MANTOVANI, A