Turn Around Freezing: Community-Living Turning Behavior in People with Parkinson's Disease.
Turn Around Freezing: Community-Living Turning Behavior in People with Parkinson's Disease.
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DOI：
10.3389/fneur.2018.00018
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发表时间：
2018
影响因子：
3.4
通讯作者：
Hausdorff JM
中科院分区：
文献类型：
--
作者：
Mancini M;Weiss A;Herman T;Hausdorff JM
行走时转身困难在帕金森氏病(PD)患者中很常见。这种困难经常导致严重的残疾、摔倒和功能丧失；此外，转身是导致步态冻结(雾)的常见触发因素。我们假设，有雾和无雾的帕金森病患者在日常生活中行走时转向活动的数量和质量会有所不同。在这里，我们首次调查了日常生活中的转动质量，因为它与使用单一惯性传感器的帕金森病患者的雾化有关。94例帕金森病患者(其中25例有雾)在正常的日常活动中佩带惯性传感器，连续3 天。一种算法识别行走的周期，并计算转弯的次数和质量指标。在家中翻转的质量，而不是数量，在冰柜中与非冰柜中不同。两组转数(冷冻组19.3 ± 9.2/30 min，非冷冻组22.4 ± 12.9/30 min；p = 0.194)相似。与非冷冻室相比，冷冻室的转身质量的某些方面，特别是平均急动度、内侧急动度的平均值和变异性显著更高(p <； 0.05)。有趣的是，与没有雾的受试者相比，有雾的受试者在转弯角度较大的转弯时表现出特定的转弯差异。这些发现表明，与没有冰冻的受试者相比，有雾的受试者在日常活动中转向受试者的功能受损。因此，临床决策和康复评估可能受益于测量帕金森病患者日常活动期间的转身活动质量。
Difficulty in turning while walking is common among patients with Parkinson’s disease (PD). This difficulty often leads to significant disability, falls, and loss of function; moreover, turning is a common trigger for freezing of gait (FoG). We hypothesized that the quantity and quality of turning mobility while walking during daily life would be different among subjects with PD with and without FoG. Here, we investigated, for the first time, the turning quality during daily life as it relates to FoG in people with PD using a single inertial sensor. Ninety-four subjects with PD (among whom 25 had FoG) wore an inertial sensor attached by a belt on the lower back during normal daily activity consecutively for 3 days. An algorithm identified periods of walking and calculated the number and quality metrics of turning. Quality, but not the quantity, of turning at home was different in freezers compared to the non-freezers. The number of turns (19.3 ± 9.2/30 min in freezers, 22.4 ± 12.9/30 min non-freezers; p = 0.194) was similar in the two groups. Some aspects of quality of turns, specifically mean jerkiness, mean and variability of medio-lateral jerkiness were significantly higher (p < 0.05) in the freezers, compared to non-freezers. Interestingly, subjects with FoG showed specific turning differences in the turns with larger angles compared to those without FoG. These findings suggest that turning during daily activities among patients with PD is impaired in subjects with FoG, compared to subject without freezing. As such, clinical decision-making and rehabilitation assessment may benefit from measuring the quality of turning mobility during daily activities in PD.
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影响因子：
4.1
作者：
Peterson DS;Plotnik M;Hausdorff JM;Earhart GM
通讯作者：
Earhart GM
影响因子：
2.4
作者：
Crenna, P.;Carpinella, I.;Ferrarin, M.
通讯作者：
Ferrarin, M.
影响因子：
8.6
作者：
Espay, Alberto J;Bonato, Paolo;Nahab, Fatta B;Maetzler, Walter;Dean, John M;Klucken, Jochen;Eskofier, Bjoern M;Merola, Aristide;Horak, Fay;Lang, Anthony E;Reilmann, Ralf;Giuffrida, Joe;Nieuwboer, Alice;Horne, Malcolm;Little, Max A;Litvan, Irene;Simuni, Tanya;Dorsey, E Ray;Burack, Michelle A;Kubota, Ken;Kamondi, Anita;Godinho, Catarina;Daneault, Jean-Francois;Mitsi, Georgia;Krinke, Lothar;Hausdorff, Jeffery M;Bloem, Bastiaan R;Papapetropoulos, Spyros
通讯作者：
Papapetropoulos, Spyros
影响因子：
2
作者：
Mancini, Martina;El-Gohary, Mahmoud;Horak, Fay B.
通讯作者：
Horak, Fay B.
帕金森氏病的转弯质量：预防姿势不稳定的补偿性策略？
影响因子：
5.1
作者：
Mellone S;Mancini M;King LA;Horak FB;Chiari L
通讯作者：
Chiari L