Efficacy of an insecticide paint against malaria vectors and nuisance in West Africa--part 2: field evaluation.
Efficacy of an insecticide paint against malaria vectors and nuisance in West Africa--part 2: field evaluation.
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杀虫剂涂料对西非疟疾病媒和滋扰的功效——第 2 部分：现场评估。
DOI：
10.1186/1475-2875-9-341
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发表时间：
2010-11-25
期刊：
影响因子：
3
通讯作者：
Mas-Coma S
中科院分区：
文献类型：
--
作者：
Mosqueira B;Chabi J;Chandre F;Akogbeto M;Hougard JM;Carnevale P;Mas-Coma S
据许多非洲国家报道，主要疟疾病媒冈比亚按蚊对拟除虫菊酯存在广泛的耐药性，而且当前 IRS 方法的操作缺陷表明探索病媒控制新产品和方法的便利性。杀虫剂涂料 Inesfly 5A IGR™ 含有两种有机磷酸酯 (OP)、毒死蜱和二嗪磷以及一种昆虫生长调节剂 (IGR) 吡丙醚，在西非贝宁进行了为期 12 个月的测试。田间试验在 6 个实验小屋中进行，随机分配到一层或两层 1 公斤/6 平方米的杀虫剂或对照。评估包括：（i）早期蚊子收集，（ii）蚊子释放实验，（iii）残留效力测试和（iv）距离测试。早期的蚊子收集是针对当地抗拟除虫菊酯蚊虫种群进行的。冈比亚和致倦库蚊。根据 WHOPES 第二阶段程序，评估了四项昆虫学标准：威慑、兴奋排斥、吸血抑制和死亡率。使用当地无疟疾的蚊子进行释放实验。冈比亚雌性在 CREC 昆虫馆饲养。使用参考敏感菌株进行残留功效测试和距离测试。冈比亚和Cx。致倦五线虫。治疗六个月后，实验小屋中对拟除虫菊酯具有抗药性的蚊子群体的死亡率仍然为 90-100%。九个月时，经过两层处理的小屋中按蚊的死亡率仍约为 90-93%。冈比亚和 55% 反对 Cx。致倦五线虫。无疟疾的局部蚊子释放实验在没有物理屏障的情况下产生了 90% 的吸血抑制。通过 WHO 生物测定，在经过两层处理的小屋中观察到 12 个月的长期残留功效 (60-80%)。在 1 米距离处过夜暴露长达 12 个月后，死亡率为 96-100%。杀虫剂涂料 Inesfly 5A IGR™ 在死亡率方面取得了令人鼓舞的结果，无论是直接接触还是远距离接触，其新的操作方法可能成为拟除虫菊酯抗性领域疟疾控制工作的另一个选择。将进行第三阶段研究，以评估该产品的流行病学影响和社会学接受度。
Widespread resistance of the main malaria vector Anopheles gambiae to pyrethroids reported in many African countries and operational drawbacks to current IRS methods suggest the convenience of exploring new products and approaches for vector control. Insecticide paint Inesfly 5A IGR™, containing two organophosphates (OPs), chlorpyrifos and diazinon, and one insect growth regulator (IGR), pyriproxyfen, was tested in Benin, West Africa, for 12 months. Field trials were conducted in six experimental huts that were randomly allocated to one or two layers of insecticide at 1 Kg/6 m2 or control. Evaluations included: (i) early mosquito collection, (ii) mosquito release experiments, (iii) residual efficacy tests and (iv) distance tests. Early mosquito collections were performed on local populations of pyrethroid-resistant An. gambiae and Culex quinquefasciatus. As per WHOPES phase II procedures, four entomological criteria were evaluated: deterrence, excito-repellence, blood-feeding inhibition and mortality. Mosquito release experiments were done using local malaria-free An. gambiae females reared at the CREC insectarium. Residual efficacy tests and distance tests were performed using reference susceptible strains of An. gambiae and Cx. quinquefasciatus. Six months after treatment, mortality rates were still 90-100% against pyrethroid-resistant mosquito populations in experimental huts. At nine months, mortality rates in huts treated with two layers was still about 90-93% against An. gambiae and 55% against Cx. quinquefasciatus. Malaria-free local mosquito release experiments yielded a 90% blood-feeding inhibition in the absence of a physical barrier. A long-term residual efficacy of 12 months was observed by WHO-bioassays in huts treated with two layers (60-80%). Mortality after an overnight exposition at distances of 1 meter was 96-100% for up to 12 months. The encouraging results obtained on the insecticide paint Inesfly 5A IGR™ in terms of mortality, be it in direct contact or at a distance, and its new operational approach could constitute an additional option in malaria control efforts in areas of pyrethroid resistance. Phase III studies will be performed to assess the product's epidemiological impact and sociological acceptance.
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影响因子：
3
作者：
Beier, John C.;Keating, Joseph;Githure, John I.;Macdonald, Michael B.;Impoinvil, Daniel E.;Novak, Robert J.
通讯作者：
Novak, Robert J.
影响因子：
3
作者：
Asidi, AN;Guessan, RN;Rowland, MW
通讯作者：
Rowland, MW
影响因子：
5.4
作者：
Samuelsen, H;Toé, LP;Skovmand, O
通讯作者：
Skovmand, O
影响因子：
3
作者：
Donnelly MJ;McCall PJ;Lengeler C;Bates I;D'Alessandro U;Barnish G;Konradsen F;Klinkenberg E;Townson H;Trape JF;Hastings IM;Mutero C
通讯作者：
Mutero C
影响因子：
3.2
作者：
Amelotti, Ivana;Catala, Silvia S.;Gorla, David E.
通讯作者：
Gorla, David E.