Image-guided percutaneous lipiodol-pingyangmycin suspension injection therapy for sacral chordoma.
Image-guided percutaneous lipiodol-pingyangmycin suspension injection therapy for sacral chordoma.
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DOI：
10.3348/kjr.2013.14.5.823
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发表时间：
2013-09
影响因子：
4.8
通讯作者：
Li Y
中科院分区：
文献类型：
--
作者：
Huang D;Chen Y;Zeng Q;Wu R;Li Y
一名74岁男性，因骶骨疼痛逐渐加重，于2004年5月被活检诊断为骶骨脊索瘤。在图像引导下经皮瘤内注射脂碘平阳霉素悬浮液（LPS），当骶骨疼痛复发、肿瘤增大时重复注射。在6年的随访期间，进行了三次这种治疗。CT成像和Karnofsky评分分别评价肿瘤大小和生活质量。患者在每次手术后都没有疼痛，生活质量很高，Karnofsky表现评分在80分以上。骶部肿瘤病变得到有效控制。无并发症发生。图像引导下经皮瘤内注射LPS可能是治疗骶脊索瘤的一种安全有效的方法。
A 74-year-old man presented with a progressively worsening pain in sacrum and was diagnosed to have a sacral chordoma by biopsy in May, 2004. Percutaneous intratumoral injection with lipiodol-pingyangmycin suspension (LPS) was carried out under image guidance and repeated when the pain in sacrum recurred and the tumor increased. During a 6-year follow-up period, three sessions of this treatment were executed. CT imaging and Karnofsky Performance Score were used to evaluate the size of tumor and quality of life, respectively. The patient was free of pain after each procedure and had a high quality of life with a Karnofsky Performance Score above 80 points. The tumor lesion in sacral area was effectively controlled. No complications were observed. Percutaneous intratumoral injection with LPS under image guidance may be an effective and safe alternative for the patients with sacral chordoma.
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