CKD surveillance using laboratory data from the population-based National Health and Nutrition Examination Survey (NHANES).
CKD surveillance using laboratory data from the population-based National Health and Nutrition Examination Survey (NHANES).
复制标题
DOI：
10.1053/j.ajkd.2008.07.054
复制
发表时间：
2009-03
期刊：
影响因子：
--
通讯作者：
Coresh J
中科院分区：
文献类型：
--
作者：
Castro AF;Coresh J
使用美国人群的全国代表性样本监测慢性肾脏病（CKD）是提供CKD负担程度和趋势信息的核心，这些信息将指导临床医生和公共卫生当局的疾病管理和预防计划。我们采用横断面研究设计，利用国家健康与营养调查（NHANES）数据估计CKD患病率随时间的变化。NHANES III（1988-1994）包括15，488名参与者，NHANES 1999-2004轮包括13，233名20岁以上的参与者，他们在移动的检查中心进行血清肌酐测量。CKD的早期阶段通过肾小球滤过率（GFR）定义，肾小球滤过率（GFR）通过肾脏疾病饮食改良（MDRD）研究方程和尿白蛋白/肌酐比值（ACR）估计，尿白蛋白/肌酐比值遵循国家肾脏基金会肾脏疾病结局质量倡议建立的分类系统。从1988-1994年到1999-2004年，GFR中度降低的患病率从5.4%增加到7.7%（P<0.001），GFR重度降低的患病率从0.21%增加到0.35%（P=0.02）。在CKD 3期内，18.6%（SE 1.6%）的个体应根据一套拟议的转诊标准转诊给肾病学家;糖尿病患者的转诊率最高，白人的转诊率低于其他种族-民族群体。这些调查数据表明，CKD的患病率在1988-1994年和1999-2004年之间有所增加。CKD早期阶段（CKD 1-4期）的监测应监测这些和其他趋势。
Surveillance for chronic kidney disease (CKD) using nationally representative samples of the US population is central in providing information on the magnitude and trends in CKD burden that will guide disease management and prevention planning for clinicians and public health authorities. We used a cross-sectional study design to estimate the change in prevalence of CKD over time using National Health and Nutrition Examination Survey (NHANES) data. NHANES III (1988-1994) included 15,488 participants and NHANES rounds 1999-2004 included 13,233 participants over the age of 20 years with serum creatinine measurements who were examined in a mobile examination center. Early stages of CKD were defined by glomerular filtration rate (GFR) as estimated by the Modification of Diet in Renal Disease (MDRD) Study equation and urinary albumin-to-creatinine ratio (ACR) following the classification system established by the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative. Moderately reduced GFR increased in prevalence from 5.4% to 7.7% (P<0.001) and severely reduced GFR increased from 0.21% to 0.35% (P=0.02) from 1988-1994 to 1999-2004. Within CKD stage 3, 18.6 % (SE 1.6%) of individuals should be referred to a nephrologist following a proposed set of criteria for referral; referral rates were highest for individuals with diabetes and lower among whites compared to other race-ethnicity groups. These survey data suggest that the prevalence of CKD has increased between the years of 1988-1994 and 1999-2004. Surveillance for early stages of CKD (CKD stages 1-4) should monitor these and other trends.
登录
查看更多内容
影响因子：
8.3
作者：
Fields, LE;Burt, VL;Sorlie, P
通讯作者：
Sorlie, P
影响因子：
120.7
作者：
Mokdad, AH;Ford, ES;Marks, JS
通讯作者：
Marks, JS
影响因子：
19.6
作者：
Levey, AS;Eckardt, KU;Eknoyan, G
通讯作者：
Eknoyan, G
影响因子：
39.2
作者：
Levey, Andrew S.;Coresh, Josef;Van Lente, Frederick
通讯作者：
Van Lente, Frederick
影响因子：
13.6
作者：
O'Hare, Ann M.;Bertenthal, Daniel;Walter, Louise C.
通讯作者：
Walter, Louise C.