Walking the cost-accuracy tightrope: balancing trade-offs in data-intensive genomics

Walking the cost-accuracy tightrope: balancing trade-offs in data-intensive genomics
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走成本准确性钢丝:平衡数据密集型基因组学的权衡

DOI:
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发表时间:
2019
期刊:
影响因子:
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通讯作者:
Kyle Chard
Kyle Chard
中科院分区:
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文献类型:
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作者:
K. Leung;M. Kimball;Jason Pitt;A. Woodard;Kyle Chard

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科学应用通常在成本和准确性之间进行权衡。然而,以用户能够理解这些权衡的方式来测量和预测成本和准确性是具有挑战性的。为了满足这些需求,我们提出了数据密集型基因组学应用的预测成本和准确性模型。我们使用这些模型来创建一个权衡图,研究人员可以使用它来选择性地权衡成本和准确性。
Scientific applications often exhibit a trade-off between cost and accuracy. However, measuring and predicting cost and accuracy in a way that users can understand these trade-offs is challenging. To address these needs, we present predictive cost and accuracy models for data-intensive genomics applications. We use these models to create a trade-off graph, which researchers can use to selectively trade-off cost and accuracy.
DOI: 10.1016/j.cels.2018.03.002
发表时间: 2018-03-28
期刊: Cell systems
影响因子: 9.3
作者:
Ellrott K;Bailey MH;Saksena G;Covington KR;Kandoth C;Stewart C;Hess J;Ma S;Chiotti KE;McLellan M;Sofia HJ;Hutter C;Getz G;Wheeler D;Ding L;MC3 Working Group;Cancer Genome Atlas Research Network
通讯作者: Cancer Genome Atlas Research Network