The effects of acute alcohol administration on the human brain: insights from neuroimaging.
The effects of acute alcohol administration on the human brain: insights from neuroimaging.
复制标题
急性酒精给药对人脑的影响:神经影像学的见解。
DOI:
10.1016/j.neuropharm.2013.07.039
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发表时间:
2014-09
影响因子:
4.7
通讯作者:
Gilman JM
中科院分区:
文献类型:
--
作者:
Bjork JM;Gilman JM
Over the last quarter century, researchers have peered into the living human brain to develop and refine mechanistic accounts of alcohol-induced behavior, as well as neurobiological mechanisms for development and maintenance of addiction. These in vivo neuroimaging studies generally show that acute alcohol administration affects brain structures implicated in motivation and behavior control, and that chronic intoxication is correlated with structural and functional abnormalities in these same structures, where some elements of these decrements normalize with extended sobriety. In this review, we will summarize recent findings about acute human brain responses to alcohol using neuroimaging techniques, and how they might explain behavioral effects of alcohol intoxication. We then briefly address how chronic alcohol intoxication (as inferred from cross-sectional differences between various drinking populations and controls) may yield individual brain differences between drinking subjects that may confound interpretation of acute alcohol administration effects.
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影响因子:
3.6
作者:
Crews, Fulton Timm;Boettiger, Charlotte Ann
通讯作者:
Boettiger, Charlotte Ann
DOI:
10.1098/rstb.2005.1634
发表时间:
2005-05-29
影响因子:
6.3
作者:
Beckmann, CF;DeLuca, M;Smith, SM
通讯作者:
Smith, SM
DOI:
10.1097/00000374-200204000-00017
发表时间:
2002-04-01
影响因子:
3.2
作者:
Fein, G;Di Sclafani, V;Meyerhoff, DJ
通讯作者:
Meyerhoff, DJ
影响因子:
5.5
作者:
Bouchery, Ellen E.;Harwood, Henrick J.;Brewer, Robert D.
通讯作者:
Brewer, Robert D.
影响因子:
17.7
作者:
Bjork, JM;Grant, SJ;Hommer, DW
通讯作者:
Hommer, DW