In vitro inhibition of glutathione S-transferases by several insecticides and allelochemicals in two moth species

In vitro inhibition of glutathione S-transferases by several insecticides and allelochemicals in two moth species
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多种杀虫剂和化感物质对两种蛾类谷胱甘肽 S-转移酶的体外抑制

DOI:
10.1080/09670874.2014.894216
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发表时间:
2014-01
影响因子:
1.5
通讯作者:
Liu Nannan
Liu Nannan
中科院分区:
农林科学4区
文献类型:
--
作者:
Tang Fang;Zhang Xiubo;Liu Yusheng;Gao Xiwu;Liu Nannan

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谷胱甘肽S-转移酶(GST)是昆虫体内重要的解毒酶。研究了5种杀虫剂(高效氯氰菊酯、甲氰菊酯、辛硫磷、阿维菌素、啶虫脒)和2种植物源化感物质(槲皮素、单宁酸)对杨小舟蛾(Micromelalopha troglodyta Graeser)和杨扇舟蛾(Clostera anachoreta Fabricius)GST活性的抑制作用。GST活性被抑制所有的杀虫剂和化感物质测试,这两个化感物质是最有效的抑制剂,降低GST活性在体外的剂量依赖性的方式。槲皮素和鞣酸抑制M. troglodyta和C. anachoreta表明他们的GST生化差异。
Glutathione S-transferases (GSTs) are important detoxification enzymes in insects. This study examined the inhibitory effects of five insecticides (beta-cypermethrin, fenpropathrin, phoxim, abamectin, acetamiprid) and two plant-derived allelochemicals (quercetin, tannic acid) on GST activity in Micromelalopha troglodyta (Graeser) and Clostera anachoreta (Fabricius). GST activities were suppressed by all the insecticides and allelochemicals tested; the two allelochemicals were the most potent inhibitors, reducing GST activity in vitro in a dosage-dependent manner. Kinetic analyses of GST inhibition by quercetin and tannic acid in M. troglodyta and C. anachoreta suggested biochemical differences in their GSTs.
DOI: 10.1007/978-1-4684-4466-7
发表时间: 1984-08
影响因子: 5.7
作者:
J. Crow;George P. Georghion;Tetsuo Saitô
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