New 2019 JSH guidelines and the risk of incident cardiovascular disease: The Suita Study

New 2019 JSH guidelines and the risk of incident cardiovascular disease: The Suita Study
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2019 年新 JSH 指南和心血管疾病事件风险:吹田研究

DOI:
10.1038/s41440-022-01142-5
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发表时间:
2022
影响因子:
5.4
通讯作者:
Y. Kokubo
Y. Kokubo
中科院分区:
医学2区
文献类型:
--
作者:
Ahmed Arafa;Rena Kashima;Y. Kokubo

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高血压是心血管疾病(CVD)最重要的危险因素。由于高血压的定义在不同的指南中有所不同,因此需要确定应该针对哪些血压类别来预防心血管疾病。在此,我们使用Suita研究注册的7643名参与者(30-84岁)的数据,根据2019年日本高血压学会(JSH)指南调查了BP与心血管疾病、中风和冠心病(CHD)风险之间的关联。在113,838人年内(平均随访16.6年),690名参与者患上了心血管疾病(411例中风和279例冠心病)。与正常血压(收缩压 < 120和舒张压 < 80 )相比,血压升高(SBP130-139和/或DBP 80-  ≥ )和高血压(SBP140和/或DBP ≥ 90 )与心血管疾病、中风和冠心病的风险增加。血压正常的高值(SBP120-12 9和DBP < 80 )与心血管疾病和冠心病的风险较高相关。总而言之,心血管疾病预防干预应从低于2019年JSH指南中应用的BP水平开始。
Hypertension is the most critical risk factor for cardiovascular disease (CVD). Since the definition of hypertension varies across guidelines, identifying blood pressure (BP) categories that should be targeted to prevent CVD is needed. Herein, we investigated the association between BP per the 2019 Japanese Society of Hypertension (JSH) guidelines and the risk of CVD, stroke, and coronary heart disease (CHD) using data from 7,643 participants (30–84 years) registered in the Suita Study. Within 113,838 person-years (16.6 median years of follow-up), 690 participants developed CVD (411 cases of stroke and 279 cases of CHD). Compared to normal BP (Systolic BP (SBP) < 120 and diastolic BP (DBP) < 80 mmHg), elevated BP (SBP 130–139 and/or DBP 80–89 mmHg) and hypertension (SBP ≥ 140 and/or DBP ≥ 90 mmHg) were associated with a higher risk of CVD, stroke, and CHD. High-normal BP (SBP 120–129 and DBP < 80 mmHg) was associated with a higher risk of CVD and CHD. In conclusion, CVD preventive interventions should begin at lower BP levels than those applied in the 2019 JSH guidelines.
Hisashi Fujita:“杏仁核点燃的猫对一氧化二氮的抗惊厥作用具有急性耐受性。”
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DOI: 10.4070/kcj.2021.0121
发表时间: 2021-08
影响因子: 2.9
作者:
Arafa A;Lee HH;Eshak ES;Shirai K;Liu K;Li J;Anni NS;Shim SY;Kim HC;Iso H
通讯作者: Iso H