Activated microglia do not form functional gap junctions in vivo.
Activated microglia do not form functional gap junctions in vivo.
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DOI:
10.1016/j.jneuroim.2014.02.005
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发表时间:
2014-04-15
影响因子:
3.3
通讯作者:
Scherer, Steven S.
中科院分区:
文献类型:
--
作者:
Wasseff, Sameh K.;Scherer, Steven S.
We investigated whether microglia form gap junctions with themselves, or with astrocytes, oligodendrocytes, or neurons in vivo in normal mouse brains, and in pathological conditions that induce microglial activation - brain injury, a model of Alzheimer’s disease. Although microglia are in close physical proximity to glia and neurons, they do not form functional gap junctions under these pathological conditions.
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