The role of the nucleus accumbens core in impulsive choice, timing, and reward processing.
The role of the nucleus accumbens core in impulsive choice, timing, and reward processing.
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伏隔核核心在冲动选择，时机和奖励处理中的作用。
DOI：
10.1037/a0018464
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发表时间：
2010-02
影响因子：
1.9
通讯作者：
Kirkpatrick, Kimberly
中科院分区：
文献类型：
--
作者：
Galtress, Tiffany;Kirkpatrick, Kimberly
本系列实验旨在确定伏隔核（AcbC）对延迟折扣效应的来源。大鼠被训练为冲动选择程序，在调整较小的较早奖励和固定较大的较晚奖励之间进行选择。当奖励大小相等时，acbc损伤大鼠产生适当的选择行为。奖励幅度的增加导致acbc损伤大鼠对较大的后期奖励的偏好未能增加，而较大的后期奖励持续时间的减少导致acbc损伤大鼠选择行为的正常改变。随后的峰值时间（实验2和3）和行为对比（实验4）实验表明，acbc损伤大鼠在奖励幅度变化（实验2和4）和预期奖励被忽略（实验2和3）时，激励动机下降，但在奖励延迟的预期时间（实验2和3）中表现出完整的预期时间。结果表明，伏隔核对决定奖励的激励价值至关重要，但不参与奖励延迟的时间。
The present series of experiments aimed to pinpoint the source of nucleus accumbens core (AcbC) effects on delay discounting. Rats were trained with an impulsive choice procedure between an adjusting smaller sooner reward and a fixed larger later reward. The AcbC-lesioned rats produced appropriate choice behavior when the reward magnitude was equal. An increase in reward magnitude resulted in a failure to increase preference for the larger later reward in the AcbC-lesioned rats, whereas a decrease in the larger later reward duration resulted in normal alterations in choice behavior in AcbC-lesioned rats. Subsequent experiments with a peak timing (Experiments 2 and 3) and a behavioral contrast (Experiment 4) indicated that the AcbC-lesioned rats suffered from decreased incentive motivation during changes in reward magnitude (Experiments 2 and 4) and when expected rewards were omitted (Experiments 2 and 3), but displayed intact anticipatory timing of reward delays (Experiments 2 and 3). The results indicate that the nucleus accumbens core is critical for determining the incentive value of rewards, but does not participate in the timing of reward delays.
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影响因子：
3.4
作者：
GIBBON, J;CHURCH, RM
通讯作者：
CHURCH, RM
影响因子：
2.5
作者：
Gregorios-Pippas L;Tobler PN;Schultz W
通讯作者：
Schultz W
影响因子：
2.7
作者：
Green, L;Estle, SJ
通讯作者：
Estle, SJ
影响因子：
25
作者：
Goto, Y;Grace, AA
通讯作者：
Grace, AA
DOI：
10.1037/0097-7403.20.2.135
发表时间：
1994-04-01
期刊：
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL BEHAVIOR PROCESSES
影响因子：
--
作者：
CHURCH, RM;MECK, WH;GIBBON, J
通讯作者：
GIBBON, J