Avoiding non-independence in fMRI data analysis: leave one subject out.
Avoiding non-independence in fMRI data analysis: leave one subject out.
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DOI:
10.1016/j.neuroimage.2009.10.092
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发表时间:
2010-04-01
期刊:
影响因子:
5.7
通讯作者:
Yantis, Steven
中科院分区:
文献类型:
--
作者:
Esterman, Michael;Tamber-Rosenau, Benjamin J.;Chiu, Yu-Chin;Yantis, Steven
Concerns regarding certain fMRI data analysis practices have recently evoked lively debate. The principal concern regards the issue of non-independence, in which an initial statistical test is followed by further non-independent statistical tests. In this report, we propose a simple, practical solution to reduce bias in secondary tests due to nonindependence using a leave-one-subject-out (LOSO) approach. We provide examples of this method, show how it reduces effect size inflation, and suggest that it can serve as a functional localizer when within-subject methods are impractical.
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Yantis, Steven