Gut microbiome and breast-feeding: Implications for early immune development.
Gut microbiome and breast-feeding: Implications for early immune development.
复制标题
肠道微生物组和母乳喂养：对早期免疫发育的影响。
DOI：
10.1016/j.jaci.2022.07.014
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发表时间：
2022-09
影响因子：
14.2
通讯作者：
Jarvinen, Kirsi M.
中科院分区：
文献类型：
--
作者：
Davis, Erin C.;Castagna, Vanessa P.;Sela, David A.;Hillard, Margaret A.;Lindberg, Samantha;Mantis, Nicholas J.;Seppo, Antti E.;Jarvinen, Kirsi M.
生命早期肠道微生物组的建立是一个复杂的过程，对个体的健康具有持久的影响。有几个因素会影响微生物的组装；然而，母乳喂养被认为是婴儿期肠道微生物组成最有影响力的驱动因素之一，对功能具有潜在影响。人们一直观察到母乳喂养和配方奶喂养的婴儿肠道微生物群落的差异，并推测母乳喂养与生命早期多种传染性和非传染性疾病风险降低之间的关系在一定程度上起到了调节作用。尽管对母乳喂养婴儿的肠道微生物组进行了数十年的研究，但在了解母乳如何进化以支持微生物和免疫发育方面仍存在巨大的科学差距。这篇综述将总结母乳喂养如何广泛影响生命早期肠道微生物组组成和功能的证据，并讨论特定母乳成分塑造肠道细菌定植、演替和功能的机制。
Establishment of the gut microbiome during early life is a complex process with lasting implications on an individual’s health. Several factors influence microbial assembly; however, breastfeeding is recognized as one of the most influential drivers of gut microbiome composition during infancy, with potential implications for function. Differences in gut microbial communities between breastfed and formula-fed infants have been consistently observed and are hypothesized to partially mediate the relationships between breastfeeding and decreased risk for numerous communicable and non-communicable diseases in early life. Despite decades of research on the gut microbiome of breastfed infants, there are large scientific gaps in understanding how human milk has evolved to support microbial and immune development. This review will summarize the evidence on how breastfeeding broadly impacts early life gut microbiome composition and function and discuss mechanisms by which specific human milk components shape intestinal bacterial colonization, succession, and function.
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DOI：
10.1126/science.1198469
发表时间：
2011-01-21
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Atarashi K;Tanoue T;Shima T;Imaoka A;Kuwahara T;Momose Y;Cheng G;Yamasaki S;Saito T;Ohba Y;Taniguchi T;Takeda K;Hori S;Ivanov II;Umesaki Y;Itoh K;Honda K
通讯作者：
Honda K
影响因子：
17.1
作者：
Arrieta, Marie-Claire;Stiemsma, Leah T.;Finlay, B. Brett
通讯作者：
Finlay, B. Brett
影响因子：
14.2
作者：
Adlerberth, Ingegerd;Strachan, David P.;Wold, Agnes E.
通讯作者：
Wold, Agnes E.
影响因子：
14.2
作者：
Brand, Stephanie;Teich, Rene;Renz, Harald
通讯作者：
Renz, Harald
影响因子：
4.4
作者：
Boullier, Severine;Tanguy, Myriam;Phalipon, Armelle
通讯作者：
Phalipon, Armelle