Integrating special and underserved populations in translational research: Environmental scan of adaptive capacity and preparedness of Clinical and Translational Science Award (CTSA) program hubs.
Integrating special and underserved populations in translational research: Environmental scan of adaptive capacity and preparedness of Clinical and Translational Science Award (CTSA) program hubs.
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DOI：
10.1017/cts.2022.414
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发表时间：
2022
影响因子：
2.6
通讯作者：
Volkov, Boris B.
中科院分区：
文献类型：
--
作者：
Hoyo, Veronica;Shah, Raj C.;Dave, Gaurav;Volkov, Boris B.
关键词：
新冠肺炎疫情加剧了健康差距，并使其变得更加明显。特殊和代表性不足的人口需要从一开始就完全融入到翻译研究过程中来，并一直到最后。本文介绍了临床和翻译科学奖中心适应能力和准备的环境扫描(E-SCAN)的结果和快速分析的迷你案例研究，专门针对在不同机构研究环境中整合特殊和脆弱人口的目标。在讨论调查结果和案例研究时，我们灵活运用当地适应能力框架的概念和特点，并尽可能根据电子扫描确定的挑战和做法，就如何加强这些领域的能力提出想法。尽管过去一年在疫苗开发、临床试验、诊断和整体生物医学研究方面取得了令人难以置信的成就，但这些成功继续受到我们无法将其转化为所有人口平等获得和获得的成就的阻碍。
The COVID-19 pandemic has exacerbated health disparities and rendered them acutely more visible. Special and underrepresented populations need to be fully integrated into the translational research process from the very beginning and all the way through. This article presents findings and rapid analysis mini-case studies from the Environmental Scan (E-Scan) of adaptive capacity and preparedness of Clinical and Translational Science Award hubs, specific to the goal of integrating special and vulnerable populations in different institutional research settings. In our discussion of the findings and case studies, we flexibly apply local adaptive capacity framework concepts and characteristics, and, whenever possible, we present ideas on how to enhance capacity in those areas, based on the challenges and practices identified through the E-Scan. Although the past year has recorded incredible achievements in vaccine development, clinical trials, diagnostics, and overall biomedical research, these successes continue to be hampered by our inability to turn them into achievements equally available and accessible to all populations.
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