Cerebral aneurysms: formation, progression, and developmental chronology.
Cerebral aneurysms: formation, progression, and developmental chronology.
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DOI：
10.1007/s12975-013-0294-x
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发表时间：
2014-04
影响因子：
6.9
通讯作者：
Macdonald, R. Loch
中科院分区：
文献类型：
--
作者：
Etminan, Nima;Buchholz, Bruce A.;Dreier, Rita;Bruckner, Peter;Torner, James C.;Steiger, Hans-Jakob;Haenggi, Daniel;Macdonald, R. Loch
一般人群中未破裂颅内动脉瘤（UAI）的患病率高达3%。现有的流行病学数据表明，只有一小部分的UIA进展走向破裂在个人的一生中，但随后的破裂和UIA的自然历史的替代品讨论非常有争议的目前。在UIA破裂的情况下，病死率高达50%，因此继续激发对脑动脉瘤形成和进展的发病机制的兴趣。关于脑动脉瘤按时间顺序发展的实际数据特别难以获得，直到最近，这方面的现有知识主要来自动物或数学模型或短期观察研究。在这里，我们强调了目前的数据，脑动脉瘤的形成和发展，以及一种新的方法来调查脑动脉瘤的发展年表。
The prevalence of unruptured intracranial aneurysms (UAIs) in the general population is up to 3%. Existing epidemiological data suggests that only a small fraction of UIAs progress towards rupture over the lifetime of an individual, but the surrogates for subsequent rupture and the natural history of UIAs are discussed very controversially at present. In case of rupture of an UIA, the case-fatality is up to 50%, which therefore continues to stimulate interest in the pathogenesis of cerebral aneurysm formation and progression. Actual data on the chronological development of cerebral aneurysm has been especially difficult to obtain and, until recently, the existing knowledge in this respect is mainly derived from animal or mathematical models or short-term observational studies. Here, we highlight the current data on cerebral aneurysm formation and progression as well as a novel approach to investigate the developmental chronology of cerebral aneurysms.
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影响因子：
4.1
作者：
Chang, HS
通讯作者：
Chang, HS
影响因子：
16.2
作者：
Bergmann, Olaf;Liebl, Jakob;Frisen, Jonas
通讯作者：
Frisen, Jonas
影响因子：
8.3
作者：
Hasan DM;Mahaney KB;Brown RD Jr;Meissner I;Piepgras DG;Huston J;Capuano AW;Torner JC;International Study of Unruptured Intracranial Aneurysms Investigators
通讯作者：
International Study of Unruptured Intracranial Aneurysms Investigators
影响因子：
37.8
作者：
Aoki, Tomohiro;Kataoka, Hiroharu;Hashimoto, Nobuo
通讯作者：
Hashimoto, Nobuo
影响因子：
2.9
作者：
Frenzel, Tim;Lee, Chanhung Z.;Young, William L.
通讯作者：
Young, William L.