Brucella canis discospondylitis in 33 dogs.

Brucella canis discospondylitis in 33 dogs.
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DOI:
10.3389/fvets.2022.1043610
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发表时间:
2022
影响因子:
3.2
通讯作者:
Windsor, Rebecca
Windsor, Rebecca
中科院分区:
农林科学2区
文献类型:
--
作者:
Long, Christina;Burgers, Elisabeth;Copple, Christina;Stainback, Laura;Packer, Rebecca A.;Kopf, Kelli;Schmidt, Jessica;Emch, Samantha;Windsor, Rebecca

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描述33只犬布鲁氏菌椎间盘脊柱炎(BDS)的临床和影像学表现。来自科罗拉多州和亚利桑那州四家兽医专科医院的33名客户拥有至少一项犬b类检测和脊柱诊断成像阳性的狗。回顾性分析33只BDS犬的信号、身体和神经检查结果、实验室结果、犬b型犬血清学和诊断成像。所有的影像都是由一个委员会认证的兽医神经学家检查的。x光片由一名委员会认证的兽医放射科医生审查,不知道MRI和CT的结果。31/33(94%)的狗小于5岁(中位2.5岁,平均2.9岁,范围0.5-10岁)。21/29(72%)的狗有非特异性疼痛、脊柱疼痛或跛行症状,持续时间长达3个月(中位= 6个月,平均= 8.2个月,范围5天- 4年)。只有4/28(14%)的狗发烧。21/29(72%)犬的x线片和12/18(67%)犬的MRI显示多灶性病变。25/29(86%)的犬在x线摄影上发现了光滑、圆形的中央端板溶解,定义为“穿孔”病变。7/18(39%)犬MRI表现为明显的椎体炎或无椎间盘炎的脊柱炎。患有BDS的狗通常在年轻时出现,临床症状持续时间长。影像学“穿孔”病变的识别和MRI证据表明椎体炎、脊柱炎和无椎间盘炎的椎旁炎症应增加对BDS的怀疑。BDS在美国西南部的发生频率可能会增加,有慢性脊柱疼痛和/或跛行症状的狗应该接受犬b类筛查。
To describe the clinical and imaging findings of 33 dogs with Brucella canis discospondylitis (BDS). 33 client owned dogs from four veterinary specialty hospitals within Colorado and Arizona with at least one positive B. canis test and spinal diagnostic imaging. Retrospective review of signalment, physical and neurological examination findings, laboratory results, B. canis serology, and diagnostic imaging of 33 dogs with BDS. All imaging was reviewed by a board-certified veterinary neurologist. Radiographs were reviewed by a board-certified veterinary radiologist blinded to MRI and CT findings. 31/33 (94%) dogs were <5 years old (median = 2.5 years, mean = 2.9 years, range 0.5–10 years). 21/29 (72%) dogs had signs of nonspecific pain, spinal pain, or lameness for >3 months (median = 6 months, mean = 8.2 months, range 5 days−4 years). Fever was seen in only 4/28 (14%) dogs. Multifocal lesions were evident on radiographs in 21/29 (72%) dogs and MRI in 12/18 (67%) dogs. Smooth, round, central end-plate lysis, defined as “hole punch” lesions, were identified radiographically in 25/29 (86%) dogs. Vertebral physitis or spondylitis without discitis was evident on MRI in 7/18 (39%) dogs. Dogs with BDS typically present at a young age with a long duration of clinical signs. Identification of radiographic “hole punch” lesions and MRI evidence of vertebral physitis, spondylitis, and paravertebral inflammation without discitis should increase suspicion for BDS. BDS may be increasing in frequency in the southwestern United States, and dogs with signs of chronic spinal pain and/or lameness should be screened for B. canis.
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