Regional distribution of computed tomography attenuation across the lumbar endplate.

Regional distribution of computed tomography attenuation across the lumbar endplate.
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DOI:
10.1371/journal.pone.0259001
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发表时间:
2021
期刊:
影响因子:
3.7
通讯作者:
Inoue N
Inoue N
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Segami K;Espinoza Orías AA;Miyamoto H;Kanzaki K;An HS;Inoue N

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椎体终板在椎间盘和椎体的松质骨之间形成结构边界。终板作为坚硬的骨和弹性盘之间的机械界面,是椎盘复合体中最薄弱的部分,容易发生机械故障。然而,有关脊柱终板内骨密度分布的文献相对较少。本研究的目的是研究以Hounsfield单位(HU)为单位测量的CT在腰椎终板上的三维(3D)衰减分布。本研究共使用28具新鲜冷冻腰椎标本的308块终板。对每个脊柱进行CT扫描,并使用所产生的DICOM数据来获得骨终板的HU值。每个单独的终板表面被细分为五个临床相关的地形区。根据脊柱水平、位置(上终板或下终板)和终板区域分析衰减情况。HU值以S1终板最高。上下终板比较,同一椎体内下终板的HU值显著高于上终板的HU值,同一椎体内的椎间终板的HU值显著高于同一椎体内的终板的HU。周边区的衰减显著高于中心区32.5%。周边区域比较,后区HU值明显高于前区,左区HU值明显高于右区。这项研究提供了腰椎终板区域HU分布的详细数据,这有助于了解一些终板损伤的原因,如骨折,也有助于设计椎体间内固定。
The vertebral endplate forms a structural boundary between intervertebral disc and the trabecular bone of the vertebral body. As a mechanical interface between the stiff bone and resilient disc, the endplate is the weakest portion of the vertebral-disc complex and is predisposed to mechanical failure. However, the literature concerning the bone mineral density (BMD) distribution within the spinal endplate is comparatively sparse. The objective of this study is to investigate the three-dimensional (3D) distribution of computed tomography (CT) attenuation across the lumbosacral endplate measured in Hounsfield Units (HU). A total of 308 endplates from 28 cadaveric fresh-frozen lumbosacral spines were used in this study. Each spine was CT-scanned and the resulting DICOM data was used to obtain HU values of the bone endplate. Each individual endplate surface was subdivided into five clinically-relevant topographic zones. Attenuation was analyzed by spinal levels, sites (superior or inferior endplate) and endplate region. The highest HU values were found at the S1 endplate. Comparisons between the superior and inferior endplates showed the HU values in inferior endplates were significantly higher than those in the superior endplates within the same vertebra and the HU values in endplates cranial to the disc were significantly higher than those in the endplates caudal to the disc within the same disc. Attenuation in the peripheral region was significantly higher than in the central region by 32.5%. Regional comparison within the peripheral region showed the HU values in the posterior region were significantly higher than those in the anterior region and the HU values in the left region were significantly higher than those in the right region. This study provided detailed data on the regional HU distribution across the lumbosacral endplate, which can be useful to understand causes of some endplate lesions, such as fracture, and also to design interbody instrumentation.
DOI: 10.1038/s41598-020-80676-5
发表时间: 2021-01-18
期刊: Scientific reports
影响因子: 4.6
作者:
Irie TY;Irie T;Espinoza Orías AA;Segami K;Iwasaki N;An HS;Inoue N
通讯作者: Inoue N
DOI: 10.3109/17453677008991550
发表时间: 1970-01-01
期刊: ACTA ORTHOPAEDICA SCANDINAVICA
影响因子: --
作者:
NACHEMSON, A;LEWIN, T;FREEMAN, MAR
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DOI: 10.1016/s1529-9430(03)00061-5
发表时间: 2003-07-01
期刊: The spine journal : official journal of the North American Spine Society
影响因子: --
作者:
Beutler, William J;Peppelman, Walter C Jr
通讯作者: Peppelman, Walter C Jr
DOI: 10.1007/bf02008077
发表时间: 1967-01-01
期刊: CALCIFIED TISSUE RES
影响因子: --
作者:
BELL, G. H.;DUNBAR, OLIVE;BECK, J. S.
通讯作者: BECK, J. S.
DOI: 10.1097/01.brs.0000143623.18098.e5
发表时间: 2004-11-01
期刊: SPINE
影响因子: 3
作者:
Lowe, TG;Hashim, S;Trommeter, J
通讯作者: Trommeter, J