Nonverbal communication remains untouched: No beneficial effect of symptomatic improvement on poor gesture performance in schizophrenia.
Nonverbal communication remains untouched: No beneficial effect of symptomatic improvement on poor gesture performance in schizophrenia.
复制标题
DOI：
10.1016/j.schres.2020.08.013
复制
发表时间：
2020-09
影响因子：
4.5
通讯作者：
Walther S
中科院分区：
文献类型：
--
作者：
Wüthrich F;Pavlidou A;Stegmayer K;Eisenhardt S;Moor J;Schäppi L;Vanbellingen T;Bohlhalter S;Walther S
手势是沟通的重要组成部分。精神分裂症患者的手势缺陷往往会在疾病过程中恶化，并妨碍功能结果。这种手势缺陷与运动异常、认知障碍和精神病症状有关。精神分裂症患者的未受影响的一级亲属共享一些亚临床运动和认知异常。我们的目的是调查，是否手势性能的变化与症状的改善患者，并测试未受影响的，一级亲属的纵向性能。在这项研究中，我们测量了手势的性能，使用验证测试33例患者，29个一级亲属和38个健康对照。在患者入院后不久和出院前完成测量。专家们使用手势任务的视频记录对表现进行了盲评。此外，我们在两次访视时评估了认知功能和精神病症状。亲属的手势表现比对照组差，患者的手势表现比亲属和对照组差。患者在精神病理学方面有所改善，但在随访时手势表现显著下降，而其他组的表现保持稳定。患者的手势操作比例变化与认知功能变化相关，而其他组的手势操作比例变化与认知功能变化无关。虽然症状的严重程度降低，手势赤字进一步恶化精神分裂症。这一发现表明，不同的过程导致患者非语言沟通能力差，需要新的替代治疗方法。
Gestures are an important part of communication. Patients with schizophrenia present gesture deficits that tend to deteriorate in the course of the disease and hamper functional outcome. This gesture deficit has been associated with motor abnormalities, cognitive impairment, and psychotic symptoms. Unaffected, first-degree relatives of schizophrenia patients share some subclinical motor and cognitive abnormalities. We aimed to investigate, whether gesture performance changes with symptomatic improvement in patients, and to test the longitudinal performance in unaffected, first-degree relatives. In this study, we measured gesture performance using a validated test in 33 patients, 29 first-degree relatives and 38 healthy controls. Measurements were completed shortly after admission and before discharge in patients. Performance was rated blindly by experts using video recordings of the gesture task. Additionally, we evaluated cognitive function and psychotic symptoms at both visits. Gesture performance was poorer in relatives compared to controls and poorer in patients compared to both relatives and controls. Patients showed an improvement in psychopathology but a significant decrease in gesture performance at follow-up, while performance in the other groups remained stable. Proportional change of gesture performance correlated with change of cognitive function in patients, whereas there were no correlations with change of cognitive function in the other groups. While symptom severity was reduced, the gesture deficit further deteriorated in schizophrenia. The finding argues for distinct processes contributing to poor nonverbal communication skills in patients, requiring novel alternative treatment efforts.
登录
查看更多内容
影响因子：
6.6
作者：
Lavelle M;Healey PG;McCabe R
通讯作者：
McCabe R
影响因子：
11
作者：
Rapoport, J. L.;Giedd, J. N.;Gogtay, N.
通讯作者：
Gogtay, N.
影响因子：
2.5
作者：
Hilbert, Sven;Nakagawa, Tristan T.;Buehner, Markus
通讯作者：
Buehner, Markus
影响因子：
--
作者：
Cannon, TD;Kaprio, J;Koskenvuo, M
通讯作者：
Koskenvuo, M
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y