Hair and toenail arsenic concentrations of residents living in areas with high environmental arsenic concentrations.
Hair and toenail arsenic concentrations of residents living in areas with high environmental arsenic concentrations.
复制标题
DOI：
10.1289/ehp.5455
复制
发表时间：
2003-02
影响因子：
10.4
通讯作者：
Drummer OH
中科院分区：
文献类型：
--
作者：
Hinwood AL;Sim MR;Jolley D;de Klerk N;Bastone EB;Gerostamoulos J;Drummer OH
澳大利亚的表层土壤和地下水被发现含有高浓度的砷。人类长期接触这些来源的相对重要性尚未确定。几项研究使用头发和脚趾甲作为暴露量的衡量标准，调查了长期暴露于环境砷浓度的情况。很少有人比较这些环境暴露源测量方法的差异。在这项研究中，我们旨在调查暴露于饮用水和土壤中一系列环境砷浓度的人群以及饮用水和土壤中砷浓度较低的对照人群中头发和脚趾甲砷浓度升高的危险因素。在这项研究中，我们招募了来自饮用水和居住土壤砷浓度较高地区的 153 名参与者，以及没有预期砷暴露的对照人群。暴露人群的饮用水砷浓度中位数为43.8微克/升（范围为16.0-73微克/升），土壤砷浓度中位数为92.0毫克/千克（范围为9.1-9,900毫克/千克）。对照组饮用水砷浓度中位数低于检测限，土壤砷浓度中位数为3.3 mg/kg。根据家庭饮用水和住宅土壤砷浓度对参与者进行分类。饮用水暴露组的头发砷几何平均浓度为5.52 mg/kg，土壤暴露组的几何平均头发砷浓度为3.31 mg/kg。饮用水暴露组的趾甲砷几何平均浓度为 21.7 毫克/千克，高土壤暴露组为 32.1 毫克/千克。趾甲砷浓度与饮用水和土壤砷浓度的相关性更强；然而，很可能存在严重的外部污染。与当地环境浓度相比，住宅暴露量的测量可以更好地预测头发和脚趾甲的砷浓度。
Surface soil and groundwater in Australia have been found to contain high concentrations of arsenic. The relative importance of long-term human exposure to these sources has not been established. Several studies have investigated long-term exposure to environmental arsenic concentrations using hair and toenails as the measure of exposure. Few have compared the difference in these measures of environmental sources of exposure. In this study we aimed to investigate risk factors for elevated hair and toenail arsenic concentrations in populations exposed to a range of environmental arsenic concentrations in both drinking water and soil as well as in a control population with low arsenic concentrations in both drinking water and soil. In this study, we recruited 153 participants from areas with elevated arsenic concentrations in drinking water and residential soil, as well as a control population with no anticipated arsenic exposures. The median drinking water arsenic concentrations in the exposed population were 43.8 micro g/L (range, 16.0-73 micro g/L) and median soil arsenic concentrations were 92.0 mg/kg (range, 9.1-9,900 mg/kg). In the control group, the median drinking water arsenic concentration was below the limit of detection, and the median soil arsenic concentration was 3.3 mg/kg. Participants were categorized based on household drinking water and residential soil arsenic concentrations. The geometric mean hair arsenic concentrations were 5.52 mg/kg for the drinking water exposure group and 3.31 mg/kg for the soil exposure group. The geometric mean toenail arsenic concentrations were 21.7 mg/kg for the drinking water exposure group and 32.1 mg/kg for the high-soil exposure group. Toenail arsenic concentrations were more strongly correlated with both drinking water and soil arsenic concentrations; however, there is a strong likelihood of significant external contamination. Measures of residential exposure were better predictors of hair and toenail arsenic concentrations than were local environmental concentrations.
登录
查看更多内容
影响因子：
2.5
作者：
KOONS, RD;PETERS, CA
通讯作者：
PETERS, CA
影响因子：
8.3
作者：
DIAZBARRIGA, F;SANTOS, MA;CEBRIAN, ME
通讯作者：
CEBRIAN, ME
影响因子：
2.7
作者：
TAKAGI, Y;MATSUDA, S;KANIEWSKI, A
通讯作者：
KANIEWSKI, A
DOI：
10.1080/15298669091370293
发表时间：
1990-12-01
期刊：
AMERICAN INDUSTRIAL HYGIENE ASSOCIATION JOURNAL
影响因子：
--
作者：
AGAHIAN, B;LEE, JS;JOHNS, RE
通讯作者：
JOHNS, RE
影响因子：
11.4
作者：
Liu, SP;Lu, JC;Meeker, WQ
通讯作者：
Meeker, WQ