Theoretical analyses of chiasmata using a novel chiasma graph method applied to Chinese hamsters, mice, and dog.
Theoretical analyses of chiasmata using a novel chiasma graph method applied to Chinese hamsters, mice, and dog.
复制标题
使用适用于中国仓鼠、小鼠和狗的新型交叉图方法对交叉进行理论分析。
DOI：
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
H. Imai
中科院分区：
文献类型：
--
作者：
M. Wada;H. Imai
Some basic concepts of chiasma (including chiasma distribution, chiasma frequency, interstitial and terminal chiasmata, and chiasma interference) are reexamined theoretically in the light of gene shuffling, and a new method for chiasma analysis termed the chiasma graph is proposed. Chiasma graphs are developed for three mammals with greatly different chromosome numbers: Chinese hamster (with n = 11), mice (n = 20), and a dog (n = 39). The results demonstrate that interstitial chiasmata can contribute both to gene shuffling and to the binding of bivalents, but that so-called terminal chiasmata are in fact mostly achiasmatic terminal associations, the main function of which is to bind bivalents. For this reason, terminal chiasmata should be excluded when chiasma frequency is estimated. It is also demonstrated that interstitial chiasmata distribute on bivalents randomly and uniformly, except at the centromere and telomere. Interference distance fluctuates almost randomly above a minimum value equivalent to about 1.8% of total bivalent length at diakinesis. These results indicate that chiasma formation in mammals is principally a random event. The demonstrated minimum interference distance seems consistent with the polymerization model for chiasma formation. Some cytological aspects of crossing-over are discussed with reference to the minimum interaction theory for eukaryotic chromosome evolution.
交叉干扰的聚合模型及相应的计算机模拟。
影响因子：
3.3
作者：
King,JS;Mortimer,RK
通讯作者：
Mortimer,RK
影响因子：
3.3
作者：
E. Foss;Russell Lande;Franklin W. Stahl;C. Steinberg
通讯作者：
E. Foss;Russell Lande;Franklin W. Stahl;C. Steinberg
DOI：
10.1073/pnas.85.18.6622
发表时间：
1988-09-01
影响因子：
11.1
作者：
MOYZIS, RK;BUCKINGHAM, JM;WU, JR
通讯作者：
WU, JR