Early postoperative recovery in operating room after desflurane anesthesia combined with Bispectral index (BIS) monitoring and warming in lengthy abdominal surgery: a randomized controlled study.

Early postoperative recovery in operating room after desflurane anesthesia combined with Bispectral index (BIS) monitoring and warming in lengthy abdominal surgery: a randomized controlled study.
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DOI:
10.1186/s12871-018-0577-6
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发表时间:
2018-08-17
期刊:
影响因子:
2.2
通讯作者:
Yu H
Yu H
中科院分区:
医学3区
文献类型:
--
作者:
Yu H;Zhang L;Ma Y;Yu H

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本研究旨在确定地氟烷 (DES) 麻醉结合脑电双频指数 (BIS) 监测和加温是否能有效减少接受长时间腹部手术的患者的麻醉控制手术室时间 (ACT)。 70 名 40 岁或以上、接受预计持续 3 至 5 小时的腹部手术的患者被随机分配到 DES 组 (n = 35) 或对照组 (n = 35)。 DES 组患者维持地氟烷麻醉并接受 BIS 监测和加温。对照组患者接受非地氟烷麻醉维持,BIS监测和加温的使用不是强制性的,由麻醉护理人员决定。记录术后早期恢复时间。拔管时间(8.8 ± 8.5 vs 14.7 ± 13.7 分钟,P = 0.035),睁眼时间(8.4 ± 8.6 vs 14.4 ± 13.4 分钟,P = 0.028),对命令做出响应(8.2 ± 8.5 vs 14.4 ± 13.0 分钟,P = 0.022),ACT(23.8 ± 11.4 vs 32.7 ± 15.4 分钟, P = 0.009)在DES组中显着低于对照组。两组的麻醉后监护室 (PACU) 住院时间、长时间拔管的发生率以及外科医生和麻醉师的满意度相似。此外,多变量线性回归结果显示,年轻、女性、BMI较低和非DES麻醉方案的患者导致拔管时间延长。地氟烷麻醉结合 BIS 监测和加温与长时间腹部手术的术后早期恢复相关。 ChiCTR-INR-17013333。注册日期:2017年11月11日。
This study aimed to determine whether the use of desflurane (DES) anesthesia combined with bispectral index (BIS) monitoring and warming is effective in reducing anesthesia-controlled operating room time (ACT) in patients undergoing lengthy abdominal surgery. Seventy patients, 40 years of age or older, undergoing abdominal surgery expected to last three to five hours were randomly assigned to the DES group (n = 35) or the control group (n = 35). Patients in the DES group were maintained with desflurane anesthesia and received BIS monitoring and warming. Patients in the control group were given non-desflurane anesthesia for maintenance, and the usage of BIS monitoring and warming were not mandatory and determined by anesthesia care providers. Early postoperative recovery times were recorded. The times to extubation (8.8 ± 8.5 vs 14.7 ± 13.7 min, P = 0.035), eye opening (8.4 ± 8.6 vs 14.4 ± 13.4 min, P = 0.028), responds on command (8.2 ± 8.5 vs 14.4 ± 13.0 min, P = 0.022), and the ACT (23.8 ± 11.4 vs 32.7 ± 15.4 min, P = 0.009) were significantly less in the DES group than that in the control group. The postanesthesia care unit (PACU) length of stay, incidence of prolonged extubation, and surgeon and anesthesiologist satisfaction were similar in two groups. Also, the result of multivariable linear regressions showed that patients who were younger, female, lower BMI and non-DES anesthesia regimen resulted in prolonged extubation. Desflurane anesthesia combined with BIS monitoring and warming is associated with early postoperative recovery in lengthy abdominal surgery. ChiCTR-INR-17013333. Date of registration: November 11, 2017.
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DOI: 10.1371/journal.pone.0165407
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