Condom effectiveness against non-viral sexually transmitted infections: a prospective study using electronic daily diaries.

Condom effectiveness against non-viral sexually transmitted infections: a prospective study using electronic daily diaries.
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DOI:
10.1136/sextrans-2012-050618
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发表时间:
2012-11
影响因子:
3.6
通讯作者:
Shrier LA
Shrier LA
中科院分区:
医学2区
文献类型:
--
作者:
Crosby RA;Charnigo RA;Weathers C;Caliendo AM;Shrier LA

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前瞻性评价持续正确使用乳胶避孕套预防沙眼衣原体、淋病奈瑟菌和阴道毛滴虫感染的价值。患者(N=929)参加治疗性传播感染(STI)的诊所进行了前瞻性随访长达6个月。在基线、3个月和6个月时进行尿STI核酸扩增检测。参与者被指示通过完成每个阴茎-阴道性交事件的报告来响应手持设备的日常提示。广义估计方程模型研究了3个月间隔内一贯以及一贯和正确使用避孕套与性传播感染发病率的关联。坚持使用避孕套与STI发病率无显著相关性(估计比值比[EOR]= 0.75; 95%置信区间[CI]= 0.43 -1.30; P= 0.31)。然而,与那些没有正确使用避孕套的人相比,正确使用避孕套的人估计获得性传播感染的几率低59%(EOR = 0.41; 95% CI = 0.19 - 0.90; P = 0.026)。正确和持续使用避孕套大大降低了非病毒性性传播感染的几率。
To prospectively evaluate the protective value of consistent and correct use of latex condoms against the acquisition of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis. Patients (N=929) attending clinics that treat sexually transmitted infections (STIs) were prospectively followed for up to six months. Urine STI nucleic acid amplification testing was performed at baseline, three months, and six months. Participants were instructed to respond to daily prompts from a hand-held device by completing a report for each penile-vaginal sexual intercourse event. Generalized estimating equation models examined associations of consistent as well as consistent and correct condom use with STI incidence over 3-month intervals. Consistent condom use was not significantly associated with STI incidence (Estimated Odds Ratio [EOR]=.75; 95% confidence interval [CI]=.43-1.30; P=.31). However, individuals who used condoms both correctly and consistently were estimated to have 59% lower odds of acquiring an STI (EOR = .41; 95% CI = .19-.90; P = .026), compared to those who did not. The correct as well as the consistent use of condoms greatly reduces the odds of non-viral STI acquisition.
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与使用自我收集的阴道拭子相比,实时PCR可改善阴道感染的检测。
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发表时间: 2005-09
影响因子: --
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