Biosilica formation in spicules of the sponge Suberites domuncula: synchronous expression of a gene cluster.
Biosilica formation in spicules of the sponge Suberites domuncula: synchronous expression of a gene cluster.
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海绵 Suberites domunula 针状体中生物硅的形成:基因簇的同步表达
DOI:
10.1016/j.ygeno.2005.02.005
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发表时间:
2005
期刊:
影响因子:
4.4
通讯作者:
Müller WEG
中科院分区:
文献类型:
--
作者:
Schröder HC;Perović-Ottstadt S;Grebenjuk VA;Engel S;Müller IM;Müller WEG
The formation of spicules is a complicated morphogenetic process in sponges (phylum Porifera). The primmorph system was used to demonstrate that in the demosponge Suberites domuncula the synthesis of the siliceous spicules starts intracellularly and is dependent on the concentration of silicic acid. To understand spicule formation, a cluster of genes was isolated. In the center of this cluster is the silicatein gene, which codes for the enzyme that synthesizes spicules. This gene is flanked by an ankyrin repeat gene at one side and by a tumor necrosis factor receptor-associated factor and a protein kinase gene at the other side. All genes are strongly expressed in primmorphs and intact animals after exposure to silicic acid, and this expression is restricted to those areas where the spicule formation starts or where spicules are maintained in the animals. Our observations suggest that in S. domuncula a coordinated expression of physically linked genes is essential for the synthesis of the major skeletal elements.
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DOI:
10.1007/978-1-4612-5214-6
发表时间:
1984-06
期刊:
--
影响因子:
--
作者:
T. Simpson
通讯作者:
T. Simpson
影响因子:
--
作者:
H. Schröder;A. Krasko;G. Le Pennec;T. Adell;M. Wiens;H. Hassanein;I. Müller;W. Müller
通讯作者:
W. Müller
影响因子:
14.9
作者:
THOMPSON, JD;HIGGINS, DG;GIBSON, TJ
通讯作者:
GIBSON, TJ
影响因子:
64.8
作者:
M. Maldonado;M. Úriz
通讯作者:
M. Úriz
影响因子:
4.8
作者:
Shyam S. ChauhanS;Nicholas C. Popescus;D. Ray;Robert FleischmannS;Michael M. GottesmanS;Bruce R. Troenn
通讯作者:
Bruce R. Troenn