Visualization of renal medullary hyperattenuation at unenhanced CT: what is the effect of furosemide administration?
Visualization of renal medullary hyperattenuation at unenhanced CT: what is the effect of furosemide administration?
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平扫 CT 肾髓质高密度可视化:呋塞米给药有何影响?
DOI:
10.1148/radiol.10091769
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发表时间:
2010
期刊:
影响因子:
19.7
通讯作者:
Yeh,BenjaminM
中科院分区:
文献类型:
--
作者:
Kumar,Rahi;Wang,ZhenJ;Fu,Yanjun;Forsythe,Carlos;Webb,EmilyM;Yeh,BenjaminM
PurposeTo retrospectively investigate the effects of furosemide on the visualization of renal medullary hyperattenuation at unenhanced computed tomography (CT).Materials and MethodsThis retrospective single-institution study was HIPAA compliant and approved by the institutional review board; requirement for informed consent was waived. This study identified 289 consecutive patients (152 men, 137 women; mean age, 59 years) without ureteral obstruction who underwent unenhanced scanning as part of CT urography; of these, 178 patients did not receive intravenous furosemide prior to imaging and 111 did. The presence of renal medullary hyperattenuation, renal stones, and bladder urine attenuation levels were recorded and compared between patients who did not receive furosemide prior to imaging and those who did by using the χ2and unpaired Studentttests. A multiple logistic regression model was used to evaluate independent predictors of visualization of renal medullary hyperattenuation.ResultsRenal medullary hyperattenuation was seen less commonly in patients who received furosemide (27 of 111, 24%) than in those who did not receive furosemide prior to imaging (79 of 178, 44%,P= .001). Bladder urine attenuation was lower in patients who received furosemide (−0.1 HU) compared with those who did not (6.4 HU,P< .001). A multiple logistic regression model revealed independent associations between the visualization of renal medullary hyperattenuation and the absence of furosemide administration (P= .002), younger age (P< .001), and presence of renal stones (P= .047).ConclusionFurosemide administration prior to unenhanced CT is associated with decreased visualization of renal medullary hyperattenuation.© RSNA, 2010
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通讯作者:
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