Sex differences in the incidence of severe pain events following surgery: a review of 333,000 pain scores.
Sex differences in the incidence of severe pain events following surgery: a review of 333,000 pain scores.
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DOI：
10.1111/pme.12498
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发表时间：
2014-08
期刊：
影响因子：
--
通讯作者：
Fillingim RB
中科院分区：
文献类型：
--
作者：
Tighe PJ;Riley JL 3rd;Fillingim RB
先前的工作尚未解决术后严重疼痛发作发生率的性别差异。本研究的目的是通过直接比较数字评分量表疼痛评分以及严重疼痛事件 (SPE) 的发生率来检查一系列外科手术中临床术后疼痛评分的性别差异。一项回顾性队列研究，对 1 年时间内在三级护理学术医疗中心接受非卧床手术的成年患者记录的超过 300,000 例临床疼痛评分观察结果进行了回顾性队列研究。为了检验术后第 1 天 (POD) 的 SPE 数量在控制手术后因性别而异的假设，我们根据 SPE 计数计算了性别的 Cochran-Mantel-Haenszel 统计数据，并控制了手术类型。疼痛评分是从临床护理记录中收集的，并使用数字评分量表进行记录。在女性患者中，43,806 个 POD 1 疼痛评分中有 10,989 个 (25.09%) 被认为是 SPE，而男性患者的 48,055 个 POD 1 疼痛评分中有 10,786 个 (22.45%) 被认为是 SPE。这使得女性与男性在 POD 1 上报告疼痛评分的 SPE 的总体比值比为 1.16（99% 置信区间 1.11-1.20）。在控制手术类型后，对给定疼痛观察代表女性与男性患者 SPE 的比值比进行估计，得出的比值比为 1.14（99% 置信区间，1.10-1.19）。在各种外科手术的 POD 1 上，女性患者的平均疼痛评分更高，SPE 发生率更高。
Prior work has not addressed sex differences in the incidence of severe postoperative pain episodes. The goal of this study was to examine sex differences in clinical postoperative pain scores across an array of surgical procedures using direct comparisons of numeric rating scale pain scores as well as using the incidence of severe pain events (SPEs). Retrospective cohort study of over 300,000 clinical pain score observations recorded from adult patients undergoing nonambulatory surgery at a tertiary care academic medical center over a 1-year period. To test the hypothesis that the number of SPE on postoperative day (POD) 1 differed by sex after controlling for procedure, we calculated Cochran–Mantel–Haenszel statistics of sex by count of SPE, controlling for type of surgery. Pain scores were collected from clinical nursing records where they were documented using the numeric rating scale. In female patients, 10,989 (25.09%) of 43,806 POD 1 pain scores were considered SPE compared with 10,786 (22.45%) of 48,055 POD 1 pain scores in male patients. This produced an overall odds ratio of 1.16 (99% confidence interval 1.11–1.20) for females vs males to report an SPE for a pain score on POD 1. Estimates of the odds that a given pain observation represents an SPE for female vs male patients after controlling for type of surgery yielded an odds ratio of 1.14 (99% confidence interval, 1.10–1.19). Female patients experience greater mean pain scores, as well as a higher incidence of SPE, on POD 1 for a variety of surgical procedures.
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影响因子：
7.4
作者：
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通讯作者：
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