Erythrocytes: oxygen sensors and modulators of vascular tone.
Erythrocytes: oxygen sensors and modulators of vascular tone.
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红细胞:氧传感器和血管张力调节器。
DOI:
10.1152/physiol.00038.2008
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发表时间:
2009-04
期刊:
影响因子:
8.4
通讯作者:
Sprague, Randy S.
中科院分区:
文献类型:
--
作者:
Ellsworth, Mary L.;Ellis, Christopher G.;Goldman, Daniel;Stephenson, Alan H.;Dietrich, Hans H.;Sprague, Randy S.
Through oxygen-dependent release of the vasodilator ATP, the mobile erythrocyte plays a fundamental role in matching microvascular oxygen supply with local tissue oxygen demand. Signal transduction within the erythrocyte and microvessels as well as feedback mechanisms controlling ATP release have been described. Our understanding of the impact of this novel control mechanism will rely on the integration of in vivo experiments and computational models. Erythrocytes play a fundamental role in tissue oxygen supply via the controlled release of ATP in areas of increased oxygen need.
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影响因子:
9.5
作者:
BUSSE, R;TROGISCH, G;BASSENGE, E
通讯作者:
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影响因子:
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10.1152/ajpheart.00261.2008
发表时间:
2008-10-01
影响因子:
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通讯作者:
Secomb, Timothy W.
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