Erythrocytes: oxygen sensors and modulators of vascular tone.

Erythrocytes: oxygen sensors and modulators of vascular tone.
复制标题

红细胞:氧传感器和血管张力调节器。

DOI:
10.1152/physiol.00038.2008
复制
发表时间:
2009-04
期刊:
影响因子:
8.4
通讯作者:
Sprague, Randy S.
Sprague, Randy S.
中科院分区:
医学1区
文献类型:
--
作者:
Ellsworth, Mary L.;Ellis, Christopher G.;Goldman, Daniel;Stephenson, Alan H.;Dietrich, Hans H.;Sprague, Randy S.

文献摘要

参考文献

被引文献

相似文献

通过氧依赖的血管扩张剂三磷酸腺苷的释放,流动的红细胞在匹配微血管供氧和局部组织需氧量方面起着基础性作用。已经描述了红细胞和微血管内的信号转导以及控制ATP释放的反馈机制。我们对这种新的控制机制的影响的理解将依赖于体内实验和计算模型的整合。红细胞在组织供氧中起着基础性的作用,它通过在需氧增加的区域有控制地释放三磷酸腺苷来维持组织供氧。
Through oxygen-dependent release of the vasodilator ATP, the mobile erythrocyte plays a fundamental role in matching microvascular oxygen supply with local tissue oxygen demand. Signal transduction within the erythrocyte and microvessels as well as feedback mechanisms controlling ATP release have been described. Our understanding of the impact of this novel control mechanism will rely on the integration of in vivo experiments and computational models. Erythrocytes play a fundamental role in tissue oxygen supply via the controlled release of ATP in areas of increased oxygen need.
DOI: 10.1007/bf01907912
发表时间: 1985-01-01
影响因子: 9.5
作者:
BUSSE, R;TROGISCH, G;BASSENGE, E
通讯作者: BASSENGE, E
DOI: 10.1038/nm954
发表时间: 2003-12-01
期刊: NATURE MEDICINE
影响因子: 82.9
作者:
Cosby, K;Partovi, KS;Gladwin, MT
通讯作者: Gladwin, MT
DOI: 10.1161/01.res.78.3.415
发表时间: 1996-03-01
影响因子: 20.1
作者:
Campbell, WB;Gebremedhin, D;Harder, DR
通讯作者: Harder, DR
DOI: 10.1152/ajpheart.00261.2008
发表时间: 2008-10-01
影响因子: 4.8
作者:
Arciero, Julia C.;Carlson, Brian E.;Secomb, Timothy W.
通讯作者: Secomb, Timothy W.
DOI: 10.1074/jbc.273.4.2273
发表时间: 1998-01-23
影响因子: 4.8
作者:
Bayewitch, ML;Avidor-Reiss, T;Vogel, Z
通讯作者: Vogel, Z