Efficient Designs for Event-Related Functional Magnetic Resonance Imaging with Multiple Scanning Sessions
Efficient Designs for Event-Related Functional Magnetic Resonance Imaging with Multiple Scanning Sessions
复制标题
具有多个扫描会话的事件相关功能磁共振成像的高效设计
DOI：
10.1080/03610920902947626
复制
发表时间：
2009
期刊：
影响因子：
--
通讯作者：
J. Stufken
中科院分区：
文献类型：
--
作者：
M. Kao;A. Mandal;J. Stufken
事件相关功能磁共振成像（ER-fMRI）是研究大脑对精神刺激的反应的领先技术。由于这项开创性技术的普及和高成本，高效的实验设计需求量很大。然而，ER-fMRI的复杂性使得很难获得这样的设计，它需要仔细考虑统计和实际问题，以及主要的计算工作。在这篇文章中，我们获得了有效的设计ER功能磁共振成像。与以前的研究相比，我们考虑到一个常见的做法，即受试者在实验中进行多次扫描。据我们所知，这一重要的现实从来没有被系统地研究过，用于设计选择。我们比较了几种方法，以获得有效的设计，并提出了一种新的算法，这个问题。我们的模拟结果表明，使用我们的算法，可以得到高效的设计。
Event-related functional magnetic resonance imaging (ER-fMRI) is a leading technology for studying brain activity in response to mental stimuli. Due to the popularity and high cost of this pioneering technology, efficient experimental designs are in great demand. However, the complex nature of ER-fMRI makes it difficult to obtain such designs; it requires careful consideration regarding both statistical and practical issues as well as major computational efforts. In this article, we obtain efficient designs for ER-fMRI. In contrast to previous studies, we take into account a common practice where subjects undergo multiple scanning sessions in an experiment. To the best of our knowledge, this important reality has never been studied systematically for design selection. We compare several approaches to obtain efficient designs and propose a novel algorithm for this problem. Our simulation results indicate that, using our algorithm, highly efficient designs can be obtained.
DOI：
10.1073/pnas.95.3.773
发表时间：
1998-02-03
影响因子：
11.1
作者：
Rosen, BR;Buckner, RL;Dale, AM
通讯作者：
Dale, AM